In mice with melanoma, probiotic bacteria travel from the gut and establish in tumors, where they directly stimulate immune cells to make cancer immunotherapy more effective, according to a new study led by University of ...
Apr 6, 2023
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A newly developed small-molecular radiopharmaceutical pair has successfully visualized and treated melanoma in a preclinical study, according to new research presented at the Society of Nuclear Medicine and Molecular Imaging ...
Jun 15, 2022
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Scientists at UC San Francisco (UCSF) have engineered T cells to produce a potent anti-cancer cytokine, but only when they encounter tumor cells. The immunotherapy eliminated melanoma and pancreatic cancer in mice without ...
Dec 15, 2022
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Hormone therapy is often used to treat prostate cancer that has spread to other parts of the body, but many patients develop resistance to hormone therapy, causing their disease to become more aggressive and potentially more ...
May 10, 2022
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Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. Patients with this subtype typically have poorer outcomes compared to other breast cancers, suggesting the need for improved treatments. ...
Feb 9, 2023
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Tumor cells typically alter their energy metabolism and increase glucose uptake to support their rapid division and spread. This limits glucose availability for immune cells and therefore dampens the body's anti-cancer immune ...
Feb 14, 2023
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Two independent Ludwig Cancer Research studies published in the current issue of the journal Cell show that immune cells known as neutrophils, whose abundance in the microenvironment of tumors has traditionally been associated ...
Apr 1, 2023
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One of the reasons that cancer is notoriously difficult to treat is that it can look very different for each patient. As a result, most targeted therapies only work for a fraction of cancer patients. In many cases, patients ...
Jun 3, 2022
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137
Checkpoint inhibitor drugs have been a gamechanger for many cancer patients. Yet about 70% don't respond to these medications, which work by removing the "brakes" on the immune system's response to a tumor.
Aug 1, 2022
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Researchers at the Francis Crick Institute and King's College London have revealed the complex interactions between cancer and the immune cells that surround a tumor, with the potential to inform how patients will respond ...
Jun 9, 2023
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