Researchers at Mayo Clinic's Center for Individualized Medicine have devised an immunotherapy technique that combines chimeric antigen receptor-T cell therapy, or CAR-T cell therapy, with a cancer-killing virus to more effectively ...
Apr 13, 2022
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A new chimeric antigen receptor (CAR) T-cell product had an acceptable safety profile and showed early signs of efficacy as a monotherapy and in combination with an mRNA vaccine in patients with solid tumors, according to ...
Apr 10, 2022
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Hormone therapy is often used to treat prostate cancer that has spread to other parts of the body, but many patients develop resistance to hormone therapy, causing their disease to become more aggressive and potentially more ...
May 10, 2022
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Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. Patients with this subtype typically have poorer outcomes compared to other breast cancers, suggesting the need for improved treatments. ...
Feb 9, 2023
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Tumor cells typically alter their energy metabolism and increase glucose uptake to support their rapid division and spread. This limits glucose availability for immune cells and therefore dampens the body's anti-cancer immune ...
Feb 14, 2023
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One of the reasons that cancer is notoriously difficult to treat is that it can look very different for each patient. As a result, most targeted therapies only work for a fraction of cancer patients. In many cases, patients ...
Jun 3, 2022
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Interactions between cells of the immune system and pre-cancerous cells are known to be important contributing factors to the initiation and progression of cancer. However, the dynamics of these interactions have not been ...
Apr 7, 2022
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Two independent Ludwig Cancer Research studies published in the current issue of the journal Cell show that immune cells known as neutrophils, whose abundance in the microenvironment of tumors has traditionally been associated ...
Apr 1, 2023
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30
Checkpoint inhibitor drugs have been a gamechanger for many cancer patients. Yet about 70% don't respond to these medications, which work by removing the "brakes" on the immune system's response to a tumor.
Aug 1, 2022
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521
Researchers at the Francis Crick Institute and King's College London have revealed the complex interactions between cancer and the immune cells that surround a tumor, with the potential to inform how patients will respond ...
Jun 9, 2023
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