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Coronavirus (COVID-19)

Medications

Oral nucleoside antiviral is progressing toward future pandemic preparedness

Obeldesivir (GS-5245), a novel investigational small molecule oral antiviral, represents a new tool in the ongoing effort to prepare for future pandemics.

Genetics

Genetic mutations in TLR7 and other genes tied to severe COVID-19

Whether or not a person becomes seriously ill with COVID-19 depends, among other things, on genetic factors. With this in mind, researchers from the University Hospital Bonn (UKB) and the University of Bonn, in cooperation ...

COVID-19 outbreak

Coronavirus disease 2019 (COVID-19) is the infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

A pneumonia of unknown cause detected in Wuhan, China was first reported to the World Health Organization Country Office in China on 31 December 2019 and recognised as a pandemic on 11 March 2020.

Reported illnesses have ranged from mild symptoms to severe illness and death for confirmed COVID-19 cases.

More information: WHO, CDC, global cases.

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Medications

Scientists unravel life-saving effect of dexamethasone in COVID-19

Dexamethasone is one of the most important drugs in the treatment of severe COVID-19, but patients respond very differently to the therapy. Researchers at the German Center for Neurodegenerative Diseases (DZNE) and Charité—Universitätsmedizin ...

Diseases, Conditions, Syndromes

Study: In severe COVID-19 cases, neutrophils work around the clock

The course of SARS-CoV-2 coronavirus infections depends not only on how aggressive the virus is, but also on the immune response of the infected individual. Using single-cell analyses, a group of researchers led by Samantha ...