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Immunology news

Oncology & Cancer

Study finds estrogens play a hidden role in cancers, inhibiting a key immune cell

Estrogens are known to drive tumor growth in breast cancer cells that carry its receptors, but a new study by Duke Cancer Institute researchers unexpectedly finds that estrogens play a role in fueling the growth of breast ...

Immunology

Research reveals mechanism of effector-triggered immunity

A pair of studies examining immune response in C. elegans reveal broad implications for understanding pathogen detection in higher animals and the evolutionary origins of immunity itself.

Immunology

Circadian rhythm disruption linked to lung inflammation

In a study published in the journal Frontiers in Immunology, researchers at the University of Arizona Health Sciences Center for Sleep, Circadian and Neuroscience research have explored the effects of circadian rhythm disruption ...

HIV & AIDS

'Undetectable' HIV patients could hold key to treatments

A rare group of HIV-positive people who maintain undetectable levels of the virus in their blood without medication could hold the key to new therapies for others living with the disease, says a leading genome expert.

Immunology

Novel antibodies against Klebsiella pneumoniae identified

Research at UMC Utrecht has identified 29 novel antibodies against the bacterium Klebsiella pneumoniae, an important cause of drug-resistant infections. Using genetic and functional approaches, the researchers also managed ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Diseases, Conditions, Syndromes

An eye on viruses in wastewater: Q&A with virologist

Virologist Rúbens Alves, Ph.D., came to La Jolla Institute for Immunology (LJI) to contribute to life-saving vaccine research. As a member of LJI's Shresta Lab, Alves studied how T cells fight viruses such as SARS-CoV-2 ...

Immunology

Researchers discover new role of immune cells in eye health

The eye is an immune-privileged tissue because of the need to keep blood vessels away from the central pathway of light and to restrict entry of inflammatory cells that could cause damage. This has prompted questions about ...

Oncology & Cancer

B-cells hold promise for treating glioblastoma

Harnessing the body's B-cells to fight tumors may be a promising treatment for glioblastoma, according to a Northwestern Medicine study recently published in the Journal of Clinical Investigation.

Immunology

Spring allergies have wide-ranging effects, say experts

Spring allergies bring to mind thoughts of stuffy noses and watery eyes. But allergies actually affect many different and interconnected systems within a person's body, according to the American College of Allergy, Asthma ...

Medications

Trial data underpins FDA approval of omalizumab for food allergy

Today's Food and Drug Administration approval of a supplemental biologics license for the monoclonal antibody omalizumab (Xolair) highlights the vital role of the National Institutes of Health-supported research that underpins ...

Medical research

Scientists discover hidden army of lung flu fighters

Scientists have long thought of the fluid-filled sac around our lungs merely as a cushion from external damage. Turns out, it also houses potent virus-eating cells that rush into the lungs during flu infections.

Immunology

Smoking shown to have long-term effects on the immune system

Like other factors such as age, sex, and genetics, smoking has a major impact on immune responses. This is the finding recently made by a team of scientists at the Institut Pasteur using the Milieu Intérieur cohort of 1,000 ...

Oncology & Cancer

Researchers characterize the immune landscape in cancer

Researchers have unveiled a detailed understanding of immune responses in cancer, marking a significant development in the field. The findings were published in the February 14 online issue of Cell in a paper titled "Pan-cancer ...

HIV & AIDS

New research advances potential HIV cure strategy

Published in the Journal of Infectious Diseases, new research led by the University of Minnesota Medical School offers a new avenue of hope in the fight against chronic human immunodeficiency virus (HIV) infection.

Oncology & Cancer

Exposing hiding lymphoma cells to the immune system

A study led by the group of Didier Trono at EPFL has revealed a crucial survival tactic employed by cancer cells. The scientists have identified a group of proteins, known as "KRAB zinc finger proteins" (KZFPs), that help ...

Oncology & Cancer

New strategy for safer CAR T cell therapy in lymphomas

In treating aggressive lymphomas and blood cancer (leukemia), chimeric antigen receptor T cells (CAR T cells) are increasingly being used. For this therapy, immune cells are taken from patients and programmed by means of ...