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Inflammatory disorders news

Diseases, Conditions, Syndromes

Treatment for chronic rhinitis yields significant clinical improvements

Neurent Medical, a company developing non-surgical interventions to treat chronic inflammatory sinonasal diseases, has released positive six-month results from the PARAGON clinical study in Ear, Nose & Throat Journal.

Inflammatory disorders

A faulty iron hormone in the skin may be the root cause of psoriasis

Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2–3% of the global population. The condition is characterized by red, scaly patches that impact the ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Medications

FDA approves Bimzelx for three new indications

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective ...

Diseases, Conditions, Syndromes

Houston pollen count has spiked dramatically over the last decade

New data from the Houston area reveals spiking levels of ragweed, elm and cedar elm pollen as well as mold spore counts as we enter the fall season. An allergy expert at Baylor College of Medicine breaks down this information ...

Inflammatory disorders

FDA approves Tremfya for ulcerative colitis

The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.

Inflammatory disorders

Diagnostic tool identifies puzzling inflammatory diseases in kids

RNA performs a number of biological duties, from delivering genetic information to manufacturing proteins. But RNA is also expelled from cells via cell death or active release, and can then find its way into blood plasma.

Dentistry

Altered blood markers detected in individuals with periodontitis

Individuals with periodontitis have altered concentrations of various proteins in their blood, according to a new study from Umeå University, Sweden. These findings pave the way for research into biomarkers for periodontitis ...

Inflammatory disorders

How the health of your gut microbiome can affect your skin

The skin is the largest organ of the human body. Not only does it act as the first line of defense against external stressors such as environmental toxins, pathogens and pollutants, our skin can also reveal much about our ...

Inflammatory disorders

From grave to cradle: Collagen-induced gut cell reprogramming

Most cells have a pretty normal life: they're born, they grow, they get old, and they die. But the Benjamin Buttons of the cellular world can go from old to young again in the right context. Now, researchers from Japan have ...

Psychology & Psychiatry

Current depression linked to systemic inflammation in psoriasis

Current depression is associated with systemic inflammation, specifically increased neutrophils in patients with psoriasis, especially women, according to a study published online Dec. 21 in the Journal of Investigative Dermatology.

Diseases, Conditions, Syndromes

Fatty acid affects sensitivity of psoriasis plaques to heat, pain

A common fatty acid found in the Western diet breaks down into compounds that contribute to increased temperature and pain—but not itch—sensitivity in psoriatic lesions. The finding could lead to better understanding ...

Medical research

A way to make asthma drugs last longer

For many, inhalers are a sort of miracle drug. From gasping for air one minute, to breathing normally the next, patients can experience significant relief after one or two puffs. What few people realize is that these life-saving ...

Neuroscience

Atopic dermatitis may be risk factor for new-onset migraine

Adults with atopic dermatitis (AD) have a significantly increased risk for new-onset migraine, according to a letter to the editor published online Oct. 21 in the Journal of the European Academy of Dermatology & Venereology.

Diseases, Conditions, Syndromes

Uncovering the relationship between fatty liver disease and COVID-19

Dr. Jawaher Alharthi, from the Westmead Institute and medical research, University of Sydney, Australia, and her colleagues have discovered how COVID-19 increases the risk of fatty liver disease and how the latter is increasing ...

Diseases, Conditions, Syndromes

Restless leg syndrome more common in psoriasis patients

Restless leg syndrome (RLS) is more common in psoriasis patients and is associated with more severe psoriasis, according to a study published online Dec. 5 in the International Journal of Dermatology.

Diseases, Conditions, Syndromes

Value-based outcome set developed for psoriasis

A value-based outcome set (VOS) has been developed for psoriasis, according to an article published online Dec. 7 in the Journal of the European Academy of Dermatology and Venereology.

Inflammatory disorders

Scientists develop compound that reverses gut inflammation in mice

A drug developed by Salk Institute researchers acts like a master reset switch in the intestines. The compound, called FexD, has previously been found to lower cholesterol, burn fat, and ward off colorectal cancer in mice. ...

Health

Are 'natural' skin products irritating your skin?

Sensitive skin is a pain—sometimes literally—and for skin allergy sufferers, contact with an allergen causes an itchy red rash that may last for weeks. Common skin care products such as soaps, serums and lotions (often ...

Immunology

Researchers find missing piece of the asthma puzzle

An inflammatory molecule called LIGHT, appears to be the cause of life-threatening airway damage in patients with severe asthma. According to the new research from scientists at La Jolla Institute for Immunology (LJI), therapeutics ...