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Inflammatory disorders news

Diseases, Conditions, Syndromes

Treatment for chronic rhinitis yields significant clinical improvements

Neurent Medical, a company developing non-surgical interventions to treat chronic inflammatory sinonasal diseases, has released positive six-month results from the PARAGON clinical study in Ear, Nose & Throat Journal.

Inflammatory disorders

A faulty iron hormone in the skin may be the root cause of psoriasis

Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2–3% of the global population. The condition is characterized by red, scaly patches that impact the ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Medications

FDA approves Bimzelx for three new indications

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective ...

Diseases, Conditions, Syndromes

Houston pollen count has spiked dramatically over the last decade

New data from the Houston area reveals spiking levels of ragweed, elm and cedar elm pollen as well as mold spore counts as we enter the fall season. An allergy expert at Baylor College of Medicine breaks down this information ...

Inflammatory disorders

FDA approves Tremfya for ulcerative colitis

The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.

Inflammatory disorders

Diagnostic tool identifies puzzling inflammatory diseases in kids

RNA performs a number of biological duties, from delivering genetic information to manufacturing proteins. But RNA is also expelled from cells via cell death or active release, and can then find its way into blood plasma.

Dentistry

Altered blood markers detected in individuals with periodontitis

Individuals with periodontitis have altered concentrations of various proteins in their blood, according to a new study from Umeå University, Sweden. These findings pave the way for research into biomarkers for periodontitis ...

Inflammatory disorders

How the health of your gut microbiome can affect your skin

The skin is the largest organ of the human body. Not only does it act as the first line of defense against external stressors such as environmental toxins, pathogens and pollutants, our skin can also reveal much about our ...

Immunology

How COVID-19 triggers massive inflammation

A study led by researchers at Boston Children's Hospital explains for the first time why COVID-19 causes severe inflammation in some people, leading to acute respiratory distress and multi-organ damage. Surprisingly, the ...

Obstetrics & gynaecology

Emergency cesarean causes inflammatory response

Labor and natural childbirth cause stress on a mother's body but an emergency Cesarean is associated with even more inflammatory gene expression in the placenta, new South Australian research shows.

Health

A prune—or six—a day may keep inflammation at bay

A study in postmenopausal people suggests eating nutrient-rich prunes every day may be beneficial to bone health, reducing inflammatory factors that contribute to osteoporosis. The research will be presented this week in ...

Psychology & Psychiatry

Study finds inflammation is not always linked to depression

Multiple prior studies have found higher levels of inflammation in older individuals with depression. Now, a new Penn Medicine study has found that clinically depressed older individuals, on average, don't have elevated levels ...

Medications

Living review compares treatments for atopic dermatitis

Abrocitinib, 200 mg daily, and upadacitinib, 30 mg daily, seem to be slightly better than dupilumab for atopic dermatitis, according to a living review published online March 16 in JAMA Dermatology.

Medical research

Correct mitochondrial function prevents muscle loss during aging

The loss of muscle mass and strength during aging is called sarcopenia. Affecting the elderly population, sarcopenia is a degenerative process that brings about a decrease in wellbeing and increased dependency. A growing ...

Immunology

How sugar promotes inflammation

People who consume sugar and other carbohydrates in excess over a long period of time have an increased risk of developing an autoimmune disease. In affected patients, the immune system attacks the body's own tissue and the ...

Inflammatory disorders

Bidirectional association identified for NAFLD and psoriasis

There is a bidirectional association between nonalcoholic fatty liver disease (NAFLD) and psoriasis, especially for patients younger than 40 years, according to a study published online Feb. 16 in Frontiers in Immunology.