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Inflammatory disorders news

Diseases, Conditions, Syndromes

Treatment for chronic rhinitis yields significant clinical improvements

Neurent Medical, a company developing non-surgical interventions to treat chronic inflammatory sinonasal diseases, has released positive six-month results from the PARAGON clinical study in Ear, Nose & Throat Journal.

Inflammatory disorders

A faulty iron hormone in the skin may be the root cause of psoriasis

Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2–3% of the global population. The condition is characterized by red, scaly patches that impact the ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Medications

FDA approves Bimzelx for three new indications

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective ...

Diseases, Conditions, Syndromes

Houston pollen count has spiked dramatically over the last decade

New data from the Houston area reveals spiking levels of ragweed, elm and cedar elm pollen as well as mold spore counts as we enter the fall season. An allergy expert at Baylor College of Medicine breaks down this information ...

Inflammatory disorders

FDA approves Tremfya for ulcerative colitis

The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.

Inflammatory disorders

Diagnostic tool identifies puzzling inflammatory diseases in kids

RNA performs a number of biological duties, from delivering genetic information to manufacturing proteins. But RNA is also expelled from cells via cell death or active release, and can then find its way into blood plasma.

Dentistry

Altered blood markers detected in individuals with periodontitis

Individuals with periodontitis have altered concentrations of various proteins in their blood, according to a new study from Umeå University, Sweden. These findings pave the way for research into biomarkers for periodontitis ...

Inflammatory disorders

How the health of your gut microbiome can affect your skin

The skin is the largest organ of the human body. Not only does it act as the first line of defense against external stressors such as environmental toxins, pathogens and pollutants, our skin can also reveal much about our ...

Inflammatory disorders

Patients with inflammatory skin diseases have high stress scores

About two-thirds of patients with inflammatory skin diseases have high reported stress scores, according to a letter to the editor published online Feb. 19 in the Journal of the European Academy of Dermatology and Venereology.

Inflammatory disorders

Targeting necroptosis for inflammatory myopathies

A new study has suggested that treatment to target necroptosis in muscle fibers using a necroptosis inhibitor lessens myositis-induced muscle weakness as well as muscle cell death and inflammation in the muscles. This has ...

Inflammatory disorders

Dual functions of the Interleukin-1 Receptor-Like 2 cytokine

The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in controlling infection. The receptor can recognize multiple agonists and has been implicated in the development of inflammatory ...

Diseases, Conditions, Syndromes

New insight into how atopic dermatitis develops

Atopic dermatitis, a common skin condition affecting both children and adults, is often thought of as an inflammatory disease that arises from a breakdown in the barrier function of the skin. Now a new study pinpoints a cascade ...

Psychology & Psychiatry

Sleep disturbance highly prevalent in psoriasis patients

(HealthDay)—Sleep disturbance is highly prevalent among patients with psoriasis and is associated with pruritus, anxiety, and depression, according to a study published online Jan. 12 in the Journal of the European Academy ...

Medical research

Scientists discover the secret to the longevity of naked mole-rats

Naked mole-rats (NMRs)—the longest living rodents—show remarkable resistance to aging and cancer. NMRs have long fascinated those involved in aging research and cancer research. Now, for the first time, researchers from ...

Inflammatory disorders

Structure of central inflammation switch elucidated

Researchers at the Universities of Bonn and Regensburg have elucidated the structure of a central cellular inflammatory switch. Their work shows which site of the giant protein called NLRP3 inhibitors can bind to. This opens ...

Inflammatory disorders

Scientists reveal mechanism for colon pain and inflammation

Researchers at the NYU Pain Research Center have identified a mechanism that underlies inflammation and pain in the colon, and demonstrated that blocking a key receptor from entering colon cells can inhibit inflammation and ...

Medications

Psoriasis treatments can be life-changing

If you suffer from psoriasis, vibrant, clear skin is no longer out of reach. According to Rush dermatologists, new innovative treatments can help you put your best face forward.