Cancer Cell

Oncology & Cancer

Research reveals machinery of a deadly childhood brain cancer

St. Jude Children's Research Hospital scientists have mapped the effects of aberrant biological machinery that drives a deadly brain cancer called diffuse intrinsic pontine glioma (DIPG). The research included development ...

Oncology & Cancer

Researchers make sense out of the chaos of melanoma

Melanoma is one of the most aggressive tumours, with potential for metastasis from very early stages, when lesions are just millimetres thick. Most puzzling is that these metastases occur in an apparently chaotic way, as ...

Oncology & Cancer

Inconspicuous protein key to deadly blood cancer

Five percent of acute leukemia cases are diagnosed as mixed lineage leukemia (MLL). MLL is an aggressive blood cancer that predominantly occurs in infants and has been difficult to treat. Now, researchers at Cold Spring Harbor ...

Oncology & Cancer

Solving the mystery of NPM1 in acute myeloid leukemia

Although it has long been recognized that mutations of gene NPM1 play an important role in acute myeloid leukemia, no one has determined how the normal and the mutated forms of the protein NPM1 function.

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