A new, bio-inspired drug restores the effectiveness of immune cells in fighting cancer, a team led by researchers at The University of Texas at Austin has found. In mouse models of melanoma, bladder cancer, leukemia and colon ...
Oct 14, 2023
0
75
Endometrial carcinoma, a cancer of the lining of the uterus, is the most common gynecologic malignancy in developed nations. Over the past decade, its incidence has steadily increased (approximately 1% annually) and mortality ...
Oct 12, 2023
0
51
Researchers have confirmed that blocking an immune checkpoint molecule reduces tumor size and prolongs survival in animal models of the most aggressive childhood cancer. This study, carried out by researchers from Cima and ...
Oct 11, 2023
0
1
Loss of the "housekeeping" gene methylthioadenosine phosphorylase, or MTAP, is a common event in cancer. Patients with melanoma or bladder cancer whose tumor cells lack a functioning version of the gene tend not to respond ...
Sep 28, 2023
0
0
Treating cancer with immunotherapies known as an immune checkpoint blockade (ICB) prior to surgery (so-called neoadjuvant immunotherapy) has been a rapidly growing area of research, but the scientific community is just scratching ...
Sep 28, 2023
0
20
Macrophages are a type of white blood cell that are among the body's first line of defense against infection. In addition to killing harmful microorganisms, macrophages typically can initiate a response against tumors. However, ...
Sep 26, 2023
0
49
An international team of scientists has developed a method for simultaneously detecting thousands of lipid molecules that are displayed to T cells in the human immune system.
Sep 18, 2023
0
34
Scientists from the German Cancer Research Center (DKFZ) identify a new and surprising function of a membrane protein on the surface of cancer cells: It supports and stabilizes an important "co-stimulatory" factor that enhances ...
Sep 13, 2023
0
79
Colorectal cancer (CRC) ranks second in leading causes of cancer-related deaths globally, according to the WHO. For the first time, researchers from Helmholtz Munich and the University of Technology Dresden (TU Dresden) show ...
Aug 31, 2023
0
5
Nearly half of all patients with brain metastasis experience cognitive impairment. Until now, it was thought that this was due to the physical presence of the tumor pressing on neural tissue. But this "mass effect" hypothesis ...
Aug 30, 2023
0
56
