Researchers led by Peter Carmeliet (VIB-KU Leuven) have found a novel way to normalize the dysfunctional blood vessels that are typical for tumors. Those vessels play a pivotal role in cancer metastasis, as their fragility ...
Nov 17, 2016
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Pediatric high-grade glioma is the primary cause of cancer death in children. Genesis of these tumors is believed to be driven by mutations in proteins that disrupt fundamental mechanisms governing the development of the ...
Oct 27, 2017
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When a freeway shuts down because of an accident or construction, drivers find another road to take them where they're going. Likewise, when a targeted therapy blocks a pathway that enables tumors to grow, the cells usually ...
Apr 11, 2016
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The human gene MLL is named for the mixed lineage leukemia it creates. Specifically, the gene may break apart and fuse with parts from one of a number of other genes on other chromosomes to create cancer-causing translocations. ...
Jun 14, 2017
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Scientists at the University of Southampton have found that the precise shape of an antibody makes a big difference to how it can stimulate the body's immune system to fight cancer, paving the way for much more effective ...
Dec 11, 2014
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Researchers at the Stanford Institute for Stem Cell Biology and Regenerative Medicine have devised a tool to examine how cells behave and interact in various environments of the body. They've used it to better understand ...
Nov 1, 2021
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Data from two large cancer centers in the United States have shown that the COVID-19 pandemic caused substantial disruption to clinical trials for cancer treatment and care.
Jun 15, 2022
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Three children Alejandro Gutierrez, MD, treated for leukemia during his fellowship at Boston Children's Hospital still haunt him more than a decade later. One 15-year-old boy died from the toxicity of the drugs he was given; ...
Apr 16, 2019
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A drug with the potential to reverse resistance to immunotherapy has been developed by scientists at the University of Southampton. It has shown great promise in pre-clinical models and will be available to patients with ...
Apr 13, 2015
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Writing in the January 3 issue of Cancer Cell, researchers at University of California San Diego School of Medicine report that detection of "copy editing" by a stem cell enzyme called ADAR1, which is active in more than ...
Jan 3, 2019
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