Researchers at the Children's Medical Center Research Institute at UT Southwestern (CRI) have identified a gene that contributes to the development of several childhood cancers, in a study conducted with mice designed to ...
Aug 11, 2014
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A Ludwig Cancer Research study has identified a combination of three existing drugs that significantly extends survival in mouse models of the lethal brain cancer glioblastoma multiforme (GBM).
Sep 20, 2022
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Cancers most commonly arise because of a series of two to five mutations in different genes that combine to cause a tumor. Evidence from a growing number of experiments focused on truncal mutations—the first mutations in ...
Jan 15, 2019
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T lymphocytes found in tumors and implicated in killing tumor cells cope with the shortage of oxygen and nutrients in the tumor microenvironment by using fat as the main source of energy. Promoting a switch from glucose to ...
Sep 11, 2017
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Research led by Newcastle University has allowed scientists to gain a greater understanding into an aggressive form of childhood brain cancer.
Jan 8, 2019
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In a breakthrough study published in Cancer Cell, researchers have decoded critical genetic factors in intestinal metaplasia patients, shedding light on early signs and prevention strategies for stomach cancer—often a "ticking ...
Dec 11, 2023
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An international team of researchers led by scientists at Baylor College of Medicine has new insights into the function of neurofibromin, a tumor suppressor produced by the NF1 gene. It is well known that neurofibromin keeps ...
Mar 5, 2020
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A drug already approved for use in humans may prevent invasive bladder cancer, according to a study by researchers at the Stanford University School of Medicine.
Oct 14, 2014
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Published today in Cancer Cell, results of a study directed by Joaquin Mateo, Head of the Vall d'Hebron Institute of Oncology's (VHIO) Prostate Cancer Translational Research Group, show that DNA/RNA material contained in ...
Jul 8, 2024
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One of the most frequent problems when treating cancer is that the tumors develop resistance to therapies; at that point, treatments cease to be effective at stopping tumor growth. This is especially relevant in patients ...
Feb 27, 2020
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