About half of all tumors are missing a gene called p53, which helps healthy cells prevent genetic mutations. Many of these tumors develop resistance to chemotherapy drugs that kill cells by damaging their DNA.
Oct 22, 2015
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113
Growing insights about a significant, yet poorly understood, part of the genome - the "dark matter of DNA"—have fundamentally changed the way scientists approach the study of diseases. The human genome contains about 20,000 ...
Oct 12, 2015
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558
Tumors usually grow exclusively from where their cell of origin derives. In humans, apart from some rare cases like the accidental transmission through a cut during surgery, there are no reports of contagious cancer cells. ...
Jan 14, 2019
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265
A leading cause of cancer deaths worldwide, colon cancer is famously resistant to treatment. There are many reasons for this, but one has to do with a group of persisting cancer cells in the colon that cause relapses. Conventional ...
Dec 14, 2015
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104
Scientists have found that deadly childhood brain tumours are actually 10 different diseases that should each be diagnosed and treated based on their specific genetic faults.
Sep 28, 2017
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36
Acute myeloid leukemia, or AML, is the most common acute blood cancer in adults—and one of the most difficult to treat. Scientists at Oregon Health & Science University have discovered a potential new target for stopping ...
Aug 9, 2022
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39
A team of researchers mapping a molecular atlas for ductal carcinoma in situ (DCIS) has made a major advance toward distinguishing whether the early pre-cancers in the breast will develop into invasive cancers or remain stable.
Nov 18, 2022
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60
A common polymorphism - a variation in a person's DNA sequence that is found with regularity in the general population - can lead to a chain of events that dictates how a tumor will progress in certain types of cancer, including ...
Dec 19, 2014
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While it's long been understood that predicting outcomes in patients with cancer requires considering many factors, such as patient history, genes and disease pathology, clinicians struggle with integrating this information ...
Aug 8, 2022
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403
If you walked into a cancer clinic ten years ago as a newly diagnosed patient, you'd likely get "standard of care" treatment based on the location of the cancer in your body and its stage. Make that same visit today and your ...
Jul 29, 2016
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101
