Combining genetic information from a patient's tumor cells with three-dimensional cell cultures grown from these tumors and rapidly screening approved drugs can identify the best treatment approaches in patients for whom ...
Mar 23, 2017
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A study published by researchers from Mayo Clinic Cancer Center at Mayo Clinic in Florida and Case Western, Cleveland Medical Center, investigates the reasons for decreasing remission rates for patients with non-Hodgkin lymphoma ...
May 12, 2022
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Many cancer patients undergo treatment with multiple drugs, each of which attacks cancer in a different way, so the combination fights cancer on many fronts. But more drugs mean higher risks of side effects.
Mar 23, 2023
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Scientists at Cold Spring Harbor Laboratory (CSHL) have created the first mouse model of pancreatic cancer that recreates two subtypes of the human disease. The model, published July 23, 2020 in Cancer Discovery, will help ...
Jul 23, 2020
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Cancer, particularly metastatic cancer, can be added to the list of medical conditions that pose a significant risk of worse COVID-19 outcomes , suggests a new study. Led by Boston Children's Hospital and Zhongnan Hospital ...
May 13, 2020
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Most immunotherapies, which aim to boost T cell activity, work poorly in treating estrogen receptor-positive (ER+) breast cancer. Targeting a different type of immune cell called macrophages could be a more effective approach, ...
Mar 16, 2023
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The PARP inhibitor olaparib (Lynparza) in combination with the chemotherapeutic agent temozolomide (Temodar) showed clinical efficacy in patients with relapsed small cell lung cancer (SCLC), according to results from a phase ...
Aug 16, 2019
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Drugs that target BRAF and MEK in cancer have shown promise in treating a subset of melanoma that carries a mutation in the BRAF gene, but drug resistance usually emerges, reversing the benefit of these drugs and limiting ...
Dec 18, 2018
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Scientists at the University of Glasgow have made a second significant breakthrough in the treatment of chronic myeloid leukaemia – using precision medicine to kill more than 90% of chronic myeloid leukaemia (CML) stem ...
Sep 16, 2016
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Cells that have permanently stopped multiplying, so-called senescent cells, could play an important role in the fight against cancer, according to a new study in mice by researchers at Karolinska Institutet and IRB Barcelona. ...
Nov 3, 2022
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