Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related deaths in the world. Mostly chemoresistant, PDAC so far has no effective treatment. Understanding the connective tissue, called stroma, ...
Jun 13, 2019
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Imagine the body's cells are well-behaved students in the classroom. The "teachers" are tumor suppressor genes, and they make sure cells follow the rules. But when tumor suppressor genes are away, cells may go astray.
Nov 1, 2023
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Researchers have discovered that a protein thought to only be involved in the development of neurons in the brain also plays a major role in the development and growth of pancreatic cancer. Their findings demonstrate for ...
Nov 18, 2020
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Patients whose acute myelogenous leukemia (AML) had relapsed or was resistant to chemotherapy and those who were deemed unable to tolerate chemotherapy experienced responses to the selective BCL-2 inhibitor venetoclax (Venclexta), ...
Aug 15, 2016
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Researchers from The Hospital for Sick Children (SickKids), the Ontario Institute for Cancer Research (OICR) and University Health Network (UHN) have demonstrated that by analyzing patients' blood samples, they are able to ...
Oct 24, 2023
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Scientists at The Wistar Institute described a novel mechanism through which astrocytes, the most abundant supporting cells in the brain, also promote cancer cell growth and metastasis in the brain.
Oct 9, 2019
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Over the last several years, research teams across the world have scoured the genomes of cancer cells in a quest to uncover the genes that drive tumor growth. Meticulous analyses of the many thousands of genetic mutations ...
May 6, 2016
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Lowering levels of a hormone called PTHrP can prevent metastases and improve survival in mice with pancreatic cancer and could lead to a new way to treat patients, according to a study from cancer researchers at Columbia ...
Jul 1, 2021
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With new immunotherapy treatments for melanoma, recovery rates have risen dramatically, in some cases to around 50%. But they could be much higher: A new study led by researchers at the Weizmann Institute of Science showed, ...
Sep 12, 2018
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A treatment for psoriasis could be repurposed to treat a rare but aggressive form of youth cancer, new findings from the Garvan Institute of Medical Research suggest.
Sep 18, 2019
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