Mice with a strong tendency to obesity already exhibit epigenetic changes at six weeks of age, inducing the liver to amplify its production of the enzyme DPP4 and release it into the circulation. Over the long term, this ...
Jan 10, 2017
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(HealthDay)—Resistance to the antilipolytic effect of insulin (Adipo-IR) is increased in obese individuals with normal glucose tolerance (NGT), and in those with impaired glucose tolerance (IGT) and type 2 diabetes (T2DM), ...
Jan 9, 2017
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Physical activity benefits diabetics and others with insulin resistance. One of the reasons is that a single bout of physical activity increases the effectiveness of insulin. Thus, physical activity helps to reduce the risk ...
Jan 3, 2017
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(HealthDay)—Oxidized low-density lipoprotein (ox-LDL) as a proxy for oxidative stress is associated with metabolic syndrome (MetS) and its components, according to a study published online Dec. 19 in Diabetes.
Dec 22, 2016
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Certain type 2 diabetes drugs promote weight loss, but how they do this remains poorly understood. Insight into how these drugs work in the body—and especially the brain—could help create new drugs that effectively control ...
Dec 12, 2016
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(HealthDay)—Functionally characterized variants in hepatocyte nuclear factor-1a (HNF1A) genes, which are associated with maturity-onset diabetes of the young (MODY3), are strongly associated with diabetes, according to ...
Dec 5, 2016
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Type-1 diabetes occurs when immune cells attack the pancreas. EPFL scientists have now discovered what may trigger this attack, opening new directions for treatments.
Nov 21, 2016
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(HealthDay)—Macrophage cyclooxygenase-2 (COX-2) deletion is associated with progression of diabetic nephropathy (DN), according to an experimental study published online Nov. 4 issue of Diabetes.
Nov 9, 2016
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Incapacitating specific nerves to the kidneys improves the work of insulin on another organ, the liver, according to research from Cedars-Sinai recently published in the journal Diabetes.
Nov 1, 2016
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A molecular mechanism that influences the development of fat cells has been identified by A*STAR researchers. The discovery suggests that an excessive amount of vitamin A could have a role in obesity, and the work could lead ...
Oct 21, 2016
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