Diabetes

Diabetes

PPAR-gamma antagonist imatinib improves insulin sensitivity

(HealthDay)—Imatinib (Gleevec) blocks CDK5-mediated peroxisome proliferator-activated receptor γ (PPARγ) phosphorylation as an antagonist ligand, improving insulin sensitivity and promoting browning of white adipose tissue, ...

Diseases, Conditions, Syndromes

Study examines role of hyperglycemia in COVID-19 severity

As COVID-19 continues to rage across the U.S., researchers are digging deeper into how the virus wreaks havoc on the body, especially for those with a pre-existing chronic illness.

Diabetes

Gut microbiome tied to metabolic hormones in early pregnancy

(HealthDay)—In overweight and obese women, gut microbiome composition is associated with the metabolic hormonal environment at 16 weeks of gestation, according to a study published in the May issue of Diabetes.

Diabetes

Hippocampal insulin resistance linked to neuroplasticity

(HealthDay)—Hippocampal insulin resistance may be a key mediator of cognitive deficits, independent of glycemic control, according to an experimental study published online July 27 in Diabetes.

Diabetes

No quick fix in cardiac fat metabolism from calorie cuts

(HealthDay)—Seven-day caloric and saturated fat restriction was found to increase myocardial dietary fatty acid (DFA) partitioning in individuals with impaired glucose tolerance (IGT), according to research published online ...

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