Disease Models & Mechanisms

Diseases, Conditions, Syndromes

Signaling pathways in the pathogenesis of diamond blackfan anemia

Diamond Blackfan Anemia (DBA) is a condition that is characterized by a failure of the bone marrow to produce red blood cells, congenital abnormalities, and a predisposition to cancer. Current treatment options, including ...

HIV & AIDS

The first animal model for sexual transmission of HIV

Infection by human immunodeficiency virus (HIV) causes acquired immunodeficiency syndrome (AIDS), a debilitating disorder in which progressive weakening of the immune system makes affected individuals more susceptible to ...

Medical research

Setting standards for research into Rett syndrome

There is an urgent need for new drugs to treat Rett syndrome, a rare and severe neurological disease mainly affecting girls. A bottleneck in drug development for this syndrome is a lack of clarity at the level of preclinical ...

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