Wilson disease is a genetic disorder in which copper accumulates to toxic levels in tissues, leading to neurological symptoms and liver disease. Diagnosis of the disease is challenging because symptoms can vary widely across ...
Jan 8, 2016
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High blood cholesterol is linked to an increased risk of heart disease and stroke. To identify new strategies to combat high cholesterol in genetically predisposed individuals, new preclinical models that mimic the underlying ...
Nov 19, 2015
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In the ongoing struggle to prevent and manage seasonal flu outbreaks, animal models of influenza infection are essential to gaining better understanding of innate immune response and screening for new drugs. A research team ...
Oct 1, 2014
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Immune cells known as neutrophils are recruited by chemical signals released from sites of injury and infection. Their primary purpose is to attack pathogens and recruit additional immune defenses, but these cells can also ...
May 21, 2014
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Being awake at night and dozing during the day can be a distressing early symptom of Alzheimer's disease, but how the disease disrupts our biological clocks to cause these symptoms has remained elusive.
Feb 26, 2014
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Collaborative research out of the George Washington University (GW) reveals new information on the pathogenesis of feeding and swallowing difficulties often found in children with neurodevelopmental disorders, including autism ...
Feb 19, 2014
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While some physicians tell women a small amount of alcohol is OK during pregnancy, Ben Laufer vehemently disputes any such advice – and he has the research to back it up.
Jul 19, 2013
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A team of UC Davis investigators has found that a genetic mutation may play an important role in the development of prostate cancer. The mutation of the so-called p53 (or Tp53) gene was previously implicated in late disease ...
Jun 7, 2012
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Advances in optimisation of the gene-editing technique CRISPR/Cas9 in zebrafish disease models offer a new level of accuracy and specificity previously out of reach for research into human genetic disorders.
Oct 18, 2018
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A growing aging population means that age-dependent neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, Huntington's disease and amyotrophic lateral sclerosis are affecting increasing numbers of ...
May 3, 2017
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