Genome Research

Oncology & Cancer

Mutation stands in the way of healthy blood cell maturation

In the veins, stem cells constantly mature and develop into blood cells that are necessary for the body to work properly. Now, researchers from the University of Copenhagen and EMBL in Heidelberg have discovered exactly how ...

Genetics

Systematic interaction network filtering in biobanks

While seeking targets to attack Huntington's disease, an incurable inherited neurodegenerative disorder, neurobiologists of the research group led by Professor Erich Wanker of the Max Delbrück Center for Molecular Medicine ...

Genetics

Are mosaic embryos the 'dark horse' of IVF?

Not every embryo contains 46 perfect chromosomes. Some have more, others have fewer. The result is a common abnormality known as aneuploidy, which occurs in as many as 80 percent of human embryos.

Genetics

Cancer-preventing protein finds its own way in our DNA

Geneticists from KU Leuven, Belgium, have shown that tumour protein TP53 knows exactly where to bind to our DNA to prevent cancer. Once bound to this specific DNA sequence, the protein can activate the right genes to repair ...

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