Human Molecular Genetics

Genetics

Pegylated enzyme helps in mice with urea cycle disorder

A specially engineered, long-lasting form of the enzyme arginase, which converts arginine to ornithine, reduces levels of arginine in the blood after both single and repeated doses in mice with arginase deficiency said researchers ...

Autism spectrum disorders

Zebrafish model gives new insight on autism spectrum disorder

Autism Spectrum Disorder (ASD) is a neurological condition that affects approximately two percent of people around the world. Although several genes have been linked to multiple concurring conditions of ASD, the process that ...

Genetics

Genes leave some kids prone to weakness in wrist bones

Pediatric researchers have discovered gene locations affecting bone strength in wrist bones, the most common site for fractures in children. Children who have those genetic variants may be at higher-than-average risk of wrist ...

Genetics

Tea consumption leads to epigenetic changes in women

Epigenetic changes are chemical modifications that turn our genes off or on. In a new study from Uppsala University, researchers show that tea consumption in women leads to epigenetic changes in genes that are known to interact ...

Genetics

First US success of nonhuman primate gene editing

Mice have been and will continue to be good base models for human medicinal advances. However, their size and some of their physiological differences leave them lacking in important areas of human medicine, including neurological ...

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