Human Molecular Genetics

Genetics (from Ancient Greek γενετικός genetikos, "genitive" and that from γένεσις genesis, "origin"), a discipline of biology, is the science of genes, heredity, and variation in living organisms. Genetics deals with the molecular structure and function of genes, gene behavior in context of a cell or organism (e.g. dominance and epigenetics), patterns of inheritance from parent to offspring, and gene distribution, variation and change in populations. Given that genes are universal to living organisms, genetics can be applied to the study of all living systems, from viruses and bacteria, through plants and domestic animals, to humans (as in medical genetics). The fact that living things inherit traits from their parents has been used since prehistoric times to improve crop plants and animals through selective breeding. However, the modern science of genetics, which seeks to understand the process of inheritance, only began with the work of Gregor Mendel in the mid-19th century. Although he did not know the physical basis for heredity, Mendel observed that organisms inherit traits via discrete units of inheritance, which are now called genes. Genes correspond to regions within DNA,

Publisher
Oxford University Press
Country
Great Britain
History
1992 to present
Impact factor
7.386 (200p)

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Neuroscience

Insight into brain via 'friend of fragile X' gene

We can learn a lot about somebody from the friends they hang out with. This applies to people and also to genes and proteins. Emory scientists have been investigating a gene that we will call—spoiler alert —"Friend of ...

Genetics

Tea consumption leads to epigenetic changes in women

Epigenetic changes are chemical modifications that turn our genes off or on. In a new study from Uppsala University, researchers show that tea consumption in women leads to epigenetic changes in genes that are known to interact ...

Genetics

First US success of nonhuman primate gene editing

Mice have been and will continue to be good base models for human medicinal advances. However, their size and some of their physiological differences leave them lacking in important areas of human medicine, including neurological ...

Genetics

New gene variants found in childhood body mass index

An international team of scientists has identified novel gene locations associated with childhood body mass index (BMI)—an important measurement related to childhood obesity. The meta-analysis, covering over 47,000 children, ...

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