Idiopathic pulmonary fibrosis is a devastating disease, and recently approved therapies have limited efficacy. Lungs become damaged with fibrotic scarring, and the median length of survival after diagnosis is three to five ...
Feb 24, 2016
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For the first time scientists from Umeå University show the importance of DNA damage in fine tuning of our innate immune system and hence the ability to mount the optimal inflammatory response to infections and other biological ...
Feb 18, 2015
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According to the World Health Organization, more than 1 billion people are infected with parasitic helminths worldwide, but the prevention and treatment of helminth infection remain challenging. Research led by the University ...
Apr 13, 2022
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The hepatitis C virus (HCV) is a genetically highly variable virus that mutates extensively. An effective vaccine would therefore need to evoke broadly neutralizing antibodies that not only neutralize one HCV strain, but ...
Jan 31, 2022
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Sepsis is estimated to cause 11 million deaths every year around the world. Its treatment is based on the use of antibiotics and organ support measures, but many times it fails due to unsuccessful attempts at modulating the ...
Oct 16, 2020
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New research led by the University of Birmingham suggests that skin cancer patients could have a better prognosis if their T cells send messages from five specific genes in their immune response to drugs given to treat the ...
Sep 16, 2021
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The immune protein STING has long been noted for helping protect against viruses and tumors by signaling a well-known immune molecule. Now, UT Southwestern scientists have revealed that STING also activates a separate pathway, ...
Aug 24, 2020
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Platelets, the colorless blood cells responsible for clotting, play a critical role in controlling inflammation, but their effect on the immune system is less clear. A new Yale-led study has identified a protein from platelets—Dkk-1—that ...
Feb 10, 2016
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A team of immunologists and informatics experts at the Stanford University School of Medicine has identified a distinctive pattern of gene expression that distinguishes people with a viral infection from those with a bacterial ...
Dec 15, 2015
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Scratching the skin triggers a series of immune responses culminating in an increased number of activated mast cells—immune cells involved in allergic reactions—in the small intestine, according to research conducted ...
Apr 23, 2019
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