Immunity

Oncology & Cancer

A tumor-suppressing gene can be harmful in some cancers

The TET2 tumor suppressor gene helps guard against blood cancers and perhaps protects against heart disease. Mutations in the gene affect about 1% of people over the age of 65, making them more susceptible to those diseases. ...

Immunology

Researchers describe how lungs stand guard against the flu

Influenza viruses mutate annually, making it difficult to produce vaccines that induce antibodies capable of recognizing the changing proteins on the surface of the flu virus and conferring long-term immunity.

Oncology & Cancer

Cancer-causing mutation suppresses immune system around tumours

Mutations in 'Ras' genes, which drive 25% of human cancers by causing tumour cells to grow, multiply and spread, can also protect cancer cells from the immune system, finds a new study from the Francis Crick Institute and ...

Immunology

'Double agent' cells survival factor revealed

A group of `double agent' cells, which both protect us from some infections while also contributing to tissue damage in various inflammatory conditions, could be manipulated to offer a new approach to treating conditions ...

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