In just a few years, CAR T-cell and other adoptive T-cell therapies have emerged as among the most promising forms of cancer immunotherapy. But even as these agents prove themselves against several forms of leukemia and lymphoma—and, ...
Oct 30, 2018
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Research at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) yielded new insights into the environment surrounding different types of lung tumors, and described how these complex cell ecosystems may in turn ...
Oct 16, 2018
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In the autoimmune disease systemic lupus erythematosus or SLE, the immune system produces antibodies against parts of the body itself. How cells that produce those antibodies escape the normal "checks and balances" has been ...
Oct 10, 2018
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Inflammation is one strategy your body uses to fight infection, but if it gets out of control it can kill instead of heal. In the Sept. 18 issue of Immunity, UConn Health immunologist Vijay Rathinam and colleagues show how ...
Oct 1, 2018
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Although the success or failure of radiation therapy for cancer has long been associated with the intrinsic radio-resistance or radio-sensitivity of tumor cells, a new approach is demonstrating that radiation can take credit ...
Aug 28, 2018
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Researchers at Vanderbilt University Medical Center and their colleagues are a step closer to developing a broadly effective antibody treatment against the three major Ebola viruses that cause lethal disease in humans.
Jul 30, 2018
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Arteries such as the aorta actively transport oxygenated blood, nutrients and cells throughout the body to keep our tissues functioning normally. Damage to the arteries can result in life-threatening cardiovascular diseases. ...
Jul 30, 2018
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Recent Ebola virus disease (EVD) outbreaks, including the 2013-2016 epidemic that ravaged West Africa and the 2018 outbreak in the Democratic Republic of the Congo, highlight the need for licensed treatments for this often-deadly ...
Jul 17, 2018
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New research reveals a cellular mechanism by which good bacteria can help the gut stay healthy. The study, which appears in the journal Immunity, shows that good bacteria, or the microbiota, interact with both the epithelial ...
Jul 3, 2018
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So-called "hot" tumors filled with T cells are often considered to be more sensitive to immunotherapy compared to "cold" tumors with fewer T cells, but a clear demonstration of why has eluded cancer biologists—until now. ...
Jun 28, 2018
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