JCI Insight

JCI Insight is an Gold Open Access journal that has a 2021 Impact Factor of 9.484. The Journal publishes well-executed, high-quality studies that provide meaningful contributions to the understanding of the biology and/or treatment of disease, with an emphasis on clinically relevant basic and translational research.

Publisher
American Society for Clinical Investigation
Website
https://insight.jci.org/

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Medical research

Disarming the immune system's lethal lung response

Neutrophils, the most abundant type of white blood cell, are the body's first line of defense against infection. Foreign pathogens can stress the body and activate neutrophils. When activated, neutrophils employ various weapons ...

Diseases, Conditions, Syndromes

New way to reduce progression of diabetic kidney disease discovered

A new method to reduce the progression of diabetic kidney disease, affecting 40% of people with diabetes, has been discovered by scientists. The University of Bristol-led study published today in JCI Insight, could help the ...

HIV & AIDS

Pitt study points to new opportunities for HIV treatment

Sometimes in science, answers come serendipitously, where researchers aren't expecting to find them. That's what happened to Cristian Apetrei, Ivona Pandrea and their colleagues during a recent study on human immunodeficiency ...

Oncology & Cancer

HPV-related cancers are on the rise in men

As a group, human papillomaviruses (HPVs) are the most common sexually transmitted infection in the United States. Some forms of the virus are capable of causing cancer in both men and women.

Medications

Tackling skin inflammation with vitamin D

High-dose oral vitamin D reduced skin inflammation and increased immunoprotection in patients with chemical-induced skin rashes, according to findings from a recent Northwestern Medicine clinical trial published in JCI Insight.

Parkinson's & Movement disorders

New evidence suggests link between gut health and Parkinson's disease

While previous studies suggest Parkinson's disease begins in the gut and spreads to the brain, how the process occurs has been elusive. Now, a pre-clinical study led by Duke Health researchers provides new evidence that bolsters ...

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