Journal of Biological Chemistry

Oncology & Cancer

Zinc deficiency linked to activation of Hedgehog signaling pathway

Zinc deficiency - long associated with numerous diseases, e.g. autism, lung cancer, prostate cancer, and ovarian cancers - can lead to activation of the Hedgehog signaling pathway, a biomolecular pathway that plays essential ...

Genetics

Brain development controlled by epigenetic factor

McGill researchers have discovered, for the first time, the importance of a key epigenetic regulator in the development of the hippocampus, a part of the brain associated with learning, memory and neural stem cells. Epigenetic ...

Oncology & Cancer

Scientists find gene that inadvertently promotes cancer growth

A protein that scientists at the School of Medicine discovered in pancreatic tumors may lead to a new chemotherapy that is effective against many different kinds of cancers. But an effort to turn the discovery into a new ...

Parkinson's & Movement disorders

New molecule could slow Parkinson's

Researchers have designed a molecule that, if developed into a drug, could slow the progression of Parkinson's Disease.

Inflammatory disorders

Protein linked to development of asthma

Researchers at the Medical College of Wisconsin (MCW) have linked a specific protein to the development of post-viral infection asthma, which is the first step in generating a novel type of asthma therapy designed to prevent ...

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