Journal of Biological Chemistry

Inflammatory disorders

New compounds reduce debilitating inflammation

Six Case Western Reserve scientists are part of an international team that has discovered two compounds that show promise in decreasing inflammation associated with diseases such as ulcerative colitis, arthritis and multiple ...

HIV & AIDS

Developing effective vaccines against SARS-CoV-2 and HIV

Researchers led by Raghavan Varadarajan, professor at the Molecular Biophysics Unit, Indian Institute of Science (IISc), are working toward developing effective vaccine strategies against two viruses: SARS-CoV-2 and HIV.

HIV & AIDS

Hydrogen sulphide gas suppresses HIV infection

Researchers at the Indian Institute of Science (IISc) and their collaborators have identified a key role played by hydrogen sulfide (H2S) gas in suppressing the human immunodeficiency virus (HIV). Increased H2S was found ...

Medical research

Large transporter protein linked to schizophrenia

Scientists have suspected mutations in a cellular cholesterol transport protein are associated with psychiatric disorders, but have found it difficult to prove this and to pinpoint how it happens. Now, Kazumitsu Ueda of Kyoto ...

Inflammatory disorders

Protein linked to development of asthma

Researchers at the Medical College of Wisconsin (MCW) have linked a specific protein to the development of post-viral infection asthma, which is the first step in generating a novel type of asthma therapy designed to prevent ...

Oncology & Cancer

Zinc deficiency linked to activation of Hedgehog signaling pathway

Zinc deficiency - long associated with numerous diseases, e.g. autism, lung cancer, prostate cancer, and ovarian cancers - can lead to activation of the Hedgehog signaling pathway, a biomolecular pathway that plays essential ...

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