Journal of Biological Chemistry

Oncology & Cancer

Zinc deficiency linked to activation of Hedgehog signaling pathway

Zinc deficiency - long associated with numerous diseases, e.g. autism, lung cancer, prostate cancer, and ovarian cancers - can lead to activation of the Hedgehog signaling pathway, a biomolecular pathway that plays essential ...

Oncology & Cancer

Research finds new Rx target for childhood cancer

Research led by Michael Lan, Ph.D., Professor of Pediatrics and Genetics at LSU Health New Orleans School of Medicine, found that a compound named 5'-iodotubercidin (5'-IT) suppresses the growth of neuroblastoma cells and ...

Diabetes

Type 2 diabetes is not just about insulin

In Switzerland, more than 400,000 people suffer from type 2 diabetes, a serious metabolic disorder that is constantly increasing. Obesity, by promoting the resistance to the action of insulin—one of the hormones that regulate ...

Oncology & Cancer

Can stem cells cause and cure cancer?

Simply put, cancer is caused by mutations to genes within a cell that lead to abnormal cell growth. Finding out what causes that genetic mutation has been the holy grail of medical science for decades. Researchers at the ...

Oncology & Cancer

Researchers find link between cancer gene and obesity

Virginia Commonwealth University Massey Cancer Center researchers have discovered that a gene known to cause cancer also may play a role in determining if someone becomes obese.

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