A synthetic small molecule compound called AQAMAN can prevent and even reverse harmful protein build-up in neurons that is associated with several rare neurodegenerative disorders, including polyglutamine (or polyQ) diseases.
Jan 10, 2020
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An unpleasant tingling in the hands and feet, numbness, fuzzy and burning sensations—these symptoms may indicate a neuropathy, a disease of the nervous system. If the pain persists for several months, it is referred to ...
Jan 3, 2020
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In a paper published in the Journal of Biological Chemistry, University of Illinois at Chicago researchers and colleagues report a new mechanism for detecting foreign material during early immune responses.
Dec 3, 2019
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For the first time, the UNC School of Medicine lab of Jonathan Schisler, MS, Ph.D., linked the specific biochemical changes to a protein called CHIP to specific disease characteristics of patients with a wide range of rare ...
Nov 6, 2019
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In Switzerland, more than 400,000 people suffer from type 2 diabetes, a serious metabolic disorder that is constantly increasing. Obesity, by promoting the resistance to the action of insulin—one of the hormones that regulate ...
Sep 11, 2019
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Beta cells in pancreatic islets produce insulin to exquisitely regulate blood glucose levels and, thus, provide energy to cells throughout the body. Loss or dysfunction of the beta cells results in diabetes, a major public ...
Sep 5, 2019
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A team led by Texas A&M University's College of Veterinary Medicine & Biomedical Sciences' (CVM) researcher Dr. Stephen Safe has discovered a new pathway that may help suppress the development of glioblastoma tumors, one ...
Aug 21, 2019
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New research from the USC Viterbi School of Engineering could be key to our understanding of how the aging process works. The findings potentially pave the way for better cancer treatments and revolutionary new drugs that ...
Jul 25, 2019
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New research suggests that a particular type of carbohydrate plays an important role in regulating the blood pressure in the human body. This has been shown by researchers from the University of Copenhagen and Rigshospitalet ...
Jul 2, 2019
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Researchers at Tokyo Metropolitan Institute of Medical Sciences are reporting new insight into how the Parkinson's disease-associated protein Parkin selects its targets. Cells depend on Parkin to help get rid of damaged mitochondria. ...
May 20, 2019
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