Journal of Experimental Medicine

Medical research

A protein for the mass production of antibodies

Antibodies play a fundamental role in medicine, and antibody-mediated immune response is the ultimate target in the quest for a vaccine to defeat the current pandemic. These minute proteins, also called immunoglobulins, are ...

Genetics

DNA webs may drive lung pathology in severe COVID-19

Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published September 14 in the Journal of Experimental ...

Diseases, Conditions, Syndromes

Hepatitis B: Natural controllers shed light on immunity mechanisms

Infections in humans caused by the hepatitis B virus (HBV) represent a major public health problem. Despite the availability of effective protective vaccines, more than 250 million individuals worldwide are chronically infected ...

Diseases, Conditions, Syndromes

Researchers develop new mouse model for SARS-CoV-2

Researchers at Yale University School of Medicine have developed a new mouse model to study SARS-CoV-2 infection and disease and to accelerate testing of novel treatments and vaccines against the novel coronavirus. The study, ...

Oncology & Cancer

How breast cancer cells sneak past local immune defenses

Cold Spring Harbor Laboratory (CSHL) Associate Professor Mikala Egeblad and her colleagues describe a newly understood way by which breast cancer cells sabotage a key player in the body's immune system. That key player provides ...

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