Journal of Experimental Medicine

Oncology & Cancer

Dulling cancer therapy's double-edged sword

Researchers have discovered that killing cancer cells can actually have the unintended effect of fueling the proliferation of residual, living cancer cells, ultimately leading to aggressive tumor progression.

Immunology

Researchers discover key driver of atopic dermatitis

Severe eczema, also known as atopic dermatitis, is a chronic inflammatory skin condition that is driven by an allergic reaction. In their latest study, researchers at La Jolla Institute reveal an important player that promotes ...

Medical research

Mechanism that converts white fat to brown identified

An international team of researchers led from Karolinska Institutet have, in experiments on mice, pinpointed a mechanism for the conversion of energy-storing white fat into energy-expending brown fat. The study is published ...

Medical research

Study explores impact of obesity on bone marrow cells

New research published in the Journal of Experimental Medicine highlights the pernicious effect of obesity on the long-term health of blood-making stem cells (hematopoietic stem cells).

Immunology

Protein's role in lupus development

Northwestern Medicine scientists have demonstrated that the loss of a protein called Bim in macrophages—a type of immune cell—leads to the development of lupus-like disease in mice. The findings, published in the Journal ...

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