Journal of Experimental Medicine

Alzheimer's disease & dementia

New insight into role of amyloid beta in Alzheimer's disease

New Alzheimer's disease research details a technique that speedily measures levels in the brain of a damaging protein fragment, and insight into why mutations in a specific gene increase the risk of developing the disease.

Diseases, Conditions, Syndromes

Combination therapy cures tick-borne illness in mice

A novel combination therapy cures an emerging infectious disease, babesiosis, which is transmitted by the same ticks that transmit the agents of Lyme disease, said Yale researchers. This "radical" therapy not only clears ...

Autism spectrum disorders

Novel mouse model sheds new light on autism spectrum disorder

A new mouse model, developed by researchers at the University of Wisconsin-Madison, is the first to show that when more of a specific biological molecule moves between different parts of nerve cells in the mouse brain, it ...

Oncology & Cancer

A combined approach to treating metastatic melanoma

Oncologists at the Fred Hutchinson Cancer Research Center have successfully treated a patient with metastatic melanoma by combining two different types of immunotherapy. Cassian Yee and colleagues describe their approach ...

Immunology

Study reveals role for oxidized mitochondrial DNA in lupus

Researchers at the Baylor Institute for Immunology Research have discovered that the neutrophils of systemic lupus erythematosus (SLE) patients release oxidized DNA from their mitochondria that can stimulate an unwanted immune ...

Immunology

Researchers find new clue in lupus autoantibody production

A signaling molecule called interferon gamma could hold the key to understanding how harmful autoantibodies form in lupus patients. The finding could lead to new treatments for the chronic autoimmune disease, said researchers ...

Medical research

The up- and downside of caloric restriction for aging and health

It's already well known that a diet may have a life-extending effect. Researchers from Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in Jena, Germany, now showed that besides improving the functionality of ...

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