Journal of Experimental Medicine

Medical research

Researchers home in on what's wearing out T cells

Sometimes even cells get tired. When the T cells of your immune system are forced to deal over time with cancer or a chronic infection such as HIV or hepatitis C, they can develop 'T cell exhaustion,' becoming less effective ...

Immunology

Drug target for asthma discovered

The over-active immune cells responsible for asthma depend on the gene BCL11B to develop into mature cells, according to a study published in the Journal of Experimental Medicine. The identification of this gene's role could ...

Medical research

Malarial parasites dodge the kill

Scientists have uncovered a potential mode of parasite drug resistance in malaria infection, according to a report published in The Journal of Experimental Medicine.

Medical research

Scientists discover potential new treatment for multiple sclerosis

Scientists from the Gladstone Institutes have discovered a way to prevent the development of multiple sclerosis (MS) in mice. Using a drug that blocks the production of a certain type of immune cell linked to inflammation ...

Immunology

Finding points to a cause of chronic lung disease

Scientists have long suspected that respiratory viruses—the sort that cause common colds or bronchitis—play a critical role in the long-term development of chronic lung diseases such as asthma and chronic obstructive ...

Immunology

Ironing out oxidative stress

You're up in the mountains, the snow is blindingly white, and the sun is blazing down from the sky: ideal skiing conditions – but any skiers carrying the herpes virus might also have to reckon with the onset of cold sores ...

Oncology & Cancer

Central signaling pathway in lymphoma can be blocked successfully

Diffuse large B-cell lymphoma (DLBCL) is a blood cancer and the most common malignant condition of the lymphatic system. Although DLBCL is always fatal if left untreated, the cure rate after chemotherapy combined with antibodies ...

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