Journal of Experimental Medicine

Genetics

Insights into causes of rare genetic immune disorders

The cellular glitches underlying a rare genetic disorder called activated PI3K Delta syndrome 2 (APDS2) have been identified by researchers at the Garvan Institute of Medical Research. The disorder is caused by genetic variations ...

Genetics

New gene-editing technique reverses vision loss in mice

Researchers in China have successfully restored the vision of mice with retinitis pigmentosa, one of the major causes of blindness in humans. The study, to be published March 17 in the Journal of Experimental Medicine, uses ...

Diseases, Conditions, Syndromes

Targeting type of B cell could reduce lupus disease, study suggests

A group of University of Pittsburgh researchers has given new meaning to "knowing your ABCs." In a new study, published in the Journal of Experimental Medicine, the team showed that a type of immune cell called age-associated ...

Medical research

Finding the best models for liver and kidney disease

In two separate studies, researchers at EPFL have carried out extensive tests to develop the best mouse models for studying kidney and liver diseases. The findings provide crucial insights into both conditions, and are expected ...

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