Molecular Biology of the Cell

Medical research

Gut response to fluid flow

Flow of fluids through the gut, such as milk from an infant's diet, generates a shear stress on cells lining the intestine. Ken Lau, Ph.D., and colleagues have demonstrated that microvilli – finger-like membrane protrusions ...

Medical research

Clues point to cause of a rare fat-distribution disease

Studying a protein that gives structure to the nucleus of cells, Johns Hopkins researchers stumbled upon mutations associated with familial partial lipodystrophy (FPLD), a rare disease that disrupts normal patterns of fat ...

Oncology & Cancer

Self-perpetuating signals may drive tumor cells to spread

A team of international researchers from Duke-NUS Graduate Medical School Singapore and the Johns Hopkins University School of Medicine (USA) has identified a self-perpetuating signaling circuit inside connective tissue cells ...

Immunology

Adhesion protein optimizes border

The epithelial cells that line the intestines build a specialized cell surface—the "brush border"—that processes and absorbs nutrients, and defends against pathogens. The brush border consists of thousands of finger-like ...

page 2 from 2