Molecular Neurodegeneration

Alzheimer's disease & dementia

Tau, not amyloid-beta, triggers neuronal death process in Alzheimer's

New research points to tau, not amyloid-beta (Abeta) plaque, as the seminal event that spurs neuron death in disorders such as Alzheimer's disease. The finding, which dramatically alters the prevailing theory of Alzheimer's ...

Alzheimer's disease & dementia

Researchers identify new enzyme to fight Alzheimer's disease

An enzyme that could represent a powerful new tool for combating Alzheimer's disease has been discovered by researchers at Mayo Clinic in Florida. The enzyme—known as BACE2—destroys beta-amyloid, a toxic protein fragment ...

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