Molecular Neurodegeneration

Molecular Neurodegeneration is an open access, peer-reviewed online journal that encompasses all aspects of neurodegeneration research at the molecular and cellular levels. Neurodegenerative diseases collectively refer to neurological disorders that result from neurodegeneration and include, but are not limited to, Alzheimer's disease, Parkinson disease, Huntington disease, and prion diseases. These diseases, which are often associated with advanced aging and display varying degrees of dementia, have become a significant public health issue as humans live longer and the aging population grows larger. Recent advances in the molecular and cellular mechanisms underlying the pathogenesis of these neurodegenerative disorders have allowed for a better understanding of the disease mechanisms.

Publisher
BioMed Central
Website
http://www.molecularneurodegeneration.com
Impact factor
4.28 (2011)

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Alzheimer's disease & dementia

Tau, not amyloid-beta, triggers neuronal death process in Alzheimer's

New research points to tau, not amyloid-beta (Abeta) plaque, as the seminal event that spurs neuron death in disorders such as Alzheimer's disease. The finding, which dramatically alters the prevailing theory of Alzheimer's ...

Alzheimer's disease & dementia

Brain in a dish to learn more about Alzheimer's disease

Researchers at the Babraham Institute have found a way to replicate one of the earliest changes in Alzheimer's disease in a dish. This means that it should now be possible to find out a lot more about why it happens - and ...

Medical research

Observing brain diseases in real time

An innovative tool allows researchers to observe protein aggregation throughout the life of a worm. The development of these aggregates, which play a role in the onset of a number of neurodegenerative diseases, can now be ...

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