In the human central nervous system, there are tiny cells that—for most people, most of the time—provide important immune protection to the brain and spinal cord. Occasionally these microglia cells run terribly awry, ...
May 30, 2023
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Researchers at Karolinska Institutet in Sweden have studied the incidence and regional distribution of Alzheimer's disease biomarkers in the brains of people with Down's syndrome. The results can bring new possibilities for ...
Nov 23, 2020
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An enzyme that could represent a powerful new tool for combating Alzheimer's disease has been discovered by researchers at Mayo Clinic in Florida. The enzyme—known as BACE2—destroys beta-amyloid, a toxic protein fragment ...
Sep 17, 2012
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A study led by the Institut de Neurociències (INc-UAB) shows that APOE4, the principal genetic risk factor for the most common type of Alzheimer's disease, produces an alteration in the astrocytes' signaling mechanisms in ...
Jun 23, 2020
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New research from the University of Eastern Finland explores the role of diabetes in the cellular and molecular changes underlying Alzheimer's disease (AD). In an AD mouse model, diabetes induced through a diet rich in fats ...
Nov 18, 2020
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Researchers with the Peter O'Donnell Jr. Brain Institute at UT Southwestern have identified a new protein implicated in cell death that provides a potential therapeutic target that could prevent or delay the progress of neurodegenerative ...
Apr 27, 2021
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Researchers at the Babraham Institute have found a way to replicate one of the earliest changes in Alzheimer's disease in a dish. This means that it should now be possible to find out a lot more about why it happens - and ...
Jun 14, 2016
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More than a decade before people with Huntington's disease show symptoms, they can exhibit abnormally high levels of an immune-system molecule called interleukin-6 (IL-6), which has led many researchers to suspect IL-6 of ...
May 26, 2020
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Alzheimer's disease (AD) currently has no cure and is predicted to affect over 100 million people worldwide by 2050. Ongoing research is focused on two key neurotoxic proteins: amyloid beta (Aβ) and tau. While these proteins ...
Oct 17, 2022
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Researchers at the University of Liverpool have found that a well-established anti-epileptic drug could also be used as a treatment for neurodegenerative diseases.
Oct 13, 2015
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