Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a ...
Sep 10, 2018
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17
Certain types of breast tumors can send signals that freeze the growth of their own secondary cancers, according to a major new study co-led by Australia's Garvan Institute of Medical Research.
Aug 27, 2018
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426
As many as 50 percent of human cancer cases—across a wide variety of tissues—involve defects in a common cellular growth signaling pathway. These defects have so far defied most attempts to develop targeted therapies, ...
Aug 13, 2018
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51
When a muscle is acutely injured—whether through accidental strain or intentional weight lifting—special repair cells called fibro-adipogenic progenitors (FAPs) rush to the rescue. These cells coordinate the activity ...
Jul 26, 2018
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58
Remove tumor cells from a living organism and place them in a dish, and they will multiply even faster than before. The mystery of why this is has long stumped cancer researchers, though many have simply focused on the mutations ...
Jun 29, 2018
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217
A tumor's goal is simple: to grow, grow, grow, by making more cancer cells. But that often means growing so fast that the oxygen supply gets scarce, at which point cells within the tumor start to suffocate. Without oxygen, ...
Jun 25, 2018
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118
Scientists report finding a potentially promising treatment target for aggressive and deadly high-grade brain cancers like glioblastoma. But they also say the current lack of a drug that hits the molecular target keeps it ...
Jun 18, 2018
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153
To stop the spread of cancer, cancer cells must die. Unfortunately, many types of cancer cells seem to use innate mechanisms that block cancer cell death, therefore allowing the cancer to metastasize. While seeking to further ...
Feb 20, 2018
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188
Researchers have shown for the first time how children can inherit a severe - potentially fatal - mitochondrial disease from a healthy mother. The study, led by researchers from the MRC Mitochondrial Biology Unit at the University ...
Jan 15, 2018
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273
Tumor cells use the unfolded protein response to alter circadian rhythm, which contributes to more tumor growth, Hollings Cancer Center researchers at the Medical University of South Carolina (MUSC) find. A key part of the ...
Dec 28, 2017
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