Nature Methods

Genetics

As genomic information grows, so do security risks

As genomics information becomes more medically useful, the storage of this data in medical records will inevitably become more vulnerable, Yale researchers suggest. While large-scale genetics data is invaluable for research ...

Genetics

Linking gene expression and DNA methylation in single cells

A new method by researchers in the UK and Belgium makes it possible to study the epigenome and transcriptome of a single cell at the same time. The protocol, published in Nature Methods, helps scientists pinpoint the relationship ...

Medical research

Modeling COPD and asthma in a human small airway-on-a-chip

A research team at the Wyss Institute for Biologically Inspired Engineering at Harvard University leveraged its organ-on-a-chip technology to develop a model of the human small airway in which lung inflammatory diseases, ...

Oncology & Cancer

Flipping the switch to better see cancer cells at depths

Using a high-tech imaging method, a team of biomedical engineers at the School of Engineering & Applied Science at Washington University in St. Louis was able to see early-developing cancer cells deeper in tissue than ever ...

Medical research

Deep sea light shines on drug delivery potential

A naturally occurring bioluminescent protein found in deep sea shrimp—which helps the crustacean spit a glowing cloud at predators—has been touted as a game-changer in terms of monitoring the way drugs interact with live ...

Genetics

Complex, large-scale genome analysis made easier

Researchers at EMBL-EBI have developed a new approach to studying the effect of multiple genetic variations on different traits. The new algorithm, published in Nature Methods, makes it possible to perform genetic analysis ...

Neuroscience

Networking neurons thrive in 3-D human 'organoid'

A patient tormented by suicidal thoughts gives his psychiatrist a few strands of his hair. She derives stem cells from them to grow budding brain tissue harboring the secrets of his unique illness in a petri dish. She uses ...

Neuroscience

Neuroscientists release state-of-the-art spike-sorting software

How do researchers make sense of the mountains of data collected from recording the simultaneous activity of hundreds of neurons? Neuroscientists all over the world rely on Kilosort, software that enables them to tease apart ...

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