PLoS Genetics is a peer-reviewed, open-access journal that reflects the interdisciplinary nature of genetics and genomics research by publishing contributions in all areas of biology. The journal is indexed in PubMed Central, PubMed, and ISI Web of Knowledge, and was originally created by Wayne Frankel
Evolutionary theory says mutations are blind and occur randomly. But in the phenomenon of adaptive mutation, cells can peek under the blindfold, increasing their mutation rate in response to stress.
Aug 25, 2015
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An examination of the immune genes of the southern African Khoe-San people has revealed a completely new kind of mutation, according to researchers at the Stanford University School of Medicine. The gene variant likely contributes ...
Aug 20, 2015
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Shedding light on a decades-old controversy, scientists at the Medical University of South Carolina (MUSC) and University of California at San Diego (UCSD) published findings in PLOS Genetics this month showing that autophagy ...
Feb 13, 2020
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Neurodevelopmental disorders, including schizophrenia and autism, likely result from complex interactions that modify the effects of individual genes. In a new study, researchers evaluated the effects of over 300 pairwise ...
Feb 14, 2020
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Cell differentiation is a widely studied phenomenon forming the basis of all developmental processes including fetal growth and bone fracture healing. A series of recent studies indicates the emerging role of chondrocyte-to-osteoblast ...
Universitat Autònoma de Barcelona researchers have identified for the first time the triple mechanism that stops chromosome separation in response to situations that compromise the integrity of the genetic information. The ...
Sep 18, 2015
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Vision researchers at Columbia University Medical Center have discovered a gene that causes myopia, but only in people who spend a lot of time in childhood reading or doing other "nearwork."
Aug 31, 2015
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Cancer researchers already know of some oncogenes and other factors that promote the development of colon cancers, but they don't yet have the full picture of how these cancers originate and spread. Now researchers from the ...
Aug 05, 2015
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Elevated plasma triglyceride level is considered a risk factor for type-2 diabetes, but new findings suggest that a genetically-elevated triglyceride level is associated with protection against type-2 diabetes. Yann Klimentidis, ...
May 28, 2015
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The study of how genes are regulated and how their regulation affects human disease has the potential to generate insights into mechanisms that aren't based on variation in DNA sequence, and could even show that temporally ...
Jul 08, 2015
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