PLoS Pathogens

Diseases, Conditions, Syndromes

Scientists enlist engineered protein to battle the MERS virus

In June 2012, a 60 year-old man with flu-like symptoms walked into a private hospital in Jeddah, Saudi Arabia. Two weeks later, he died from multiple organ failure, becoming the first victim of a mysterious virus that came ...

Immunology

Immune cell variations contribute to malaria severity

At least 250 million people are infected with malaria every year, and about half a million of those die from the disease. A new study from MIT offers a possible explanation for why some people are more likely to experience ...

Diseases, Conditions, Syndromes

Pig immunology comes of age: Killer T cell responses to influenza

Researchers from The Pirbright Institute, University of Bristol, Cardiff University and University of Oxford have generated tools that allow scientists to understand a vital area of the pig immune system which was previously ...

Diseases, Conditions, Syndromes

Multiple mosquito blood meals accelerate malaria transmission

Multiple bouts of blood feeding by mosquitoes shorten the incubation period for malaria parasites and increase malaria transmission potential, according to a study published December 31 in the open-access journal PLOS Pathogens ...

Diseases, Conditions, Syndromes

How intestinal worms hinder tuberculosis vaccination

New research in mice suggests that chronic infection with intestinal worms indirectly reduces the number of cells in lymph nodes near the skin, inhibiting the immune system's response to the Bacille Calmette-Guerin (BCG) ...

Immunology

How bacteria kill host cells from the inside

A bacterial pathogen that typically multiplies outside of host cells can enter and induce the destruction of cells called macrophages, according to a study published June 20 in the open-access journal PLOS Pathogens by Anne-BĂ©atrice ...

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