The Proceedings of the National Academy of Sciences of the United States of America, usually referred to as PNAS, is the official journal of the United States National Academy of Sciences (NAS). PNAS is an important scientific journal that printed its first issue in 1915 and continues to publish highly cited research reports, commentaries, reviews, perspectives, feature articles, profiles, letters to the editor, and actions of the Academy. Coverage in PNAS broadly spans the biological, physical, and social sciences. Although most of the papers published in the journal are in the biomedical sciences, PNAS recruits papers and publishes special features in the physical and social sciences and in mathematics. PNAS is published weekly in print, and daily online in PNAS Early Edition. PNAS was established by NAS in 1914, with its first issue published in 1915. The NAS itself had been founded in 1863 as a private institution, but chartered by the US Congress, with the goal to "investigate, examine, experiment, and report upon any subject of science or art." By 1914, the Academy was well established.
Childhood leukemia is a diagnosis that no family ever wants to endure. While the treatment of most types of leukemia has improved steadily over the years, a few specific types remain very difficult to treat. One of these ...
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Cells switch fates and acquire new identities during organogenesis and regeneration as a critical trait, although the mechanisms underlying such conversions are poorly understood. The vasculature provides a biological model ...
A devastating form of childhood epilepsy that is resistant to traditional drugs may have met its match in spider venom.
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Researchers at Columbia University Irving Medical Center (CUIMC) have found new evidence of how certain transport proteins are working at the molecular level, paving the way for new, improved drugs to treat psychiatric disorders.
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Studying transthyretin amyloidoses-a group of progressive nerve and cardiac degenerative diseases caused by the buildup of misfolded transthyretin (TTR) proteins in the body-has long been hampered by the lack of animal models ...
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Glioma, a type of brain cancer, is normally treated by removing as much of the tumor as possible, followed by radiation or chemotherapy. With this treatment, patients survive an average of about 10 years, but the tumors inevitably ...
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If you're having a heart attack and you're a woman, hope a female doctor greets you in the emergency room.
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The human brain is organized of highly complex and expansive cellular and neuronal networks, but the existing scientific understanding of the developing brain is proportionately limited. Neuroengineering is an evolving field ...
A research team led by scientists from the Cancer Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has developed a novel peptide drug called FFW that could potentially stop the development ...
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Johns Hopkins Medicine scientists say they have found new evidence in lab-grown mouse brain cells, called astrocytes, that one root of Alzheimer's disease may be a simple imbalance in acid-alkaline—or pH—chemistry inside ...
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