Science Signaling

Cancer

New genetic mutation identified in melanoma cancer cells

There is strong evidence that the protein complex APC/C may function as a tumor suppressor in multiple cancers including lymphoma, colorectal and breast cancer, and now melanoma. A new study has revealed that a genetic mutation ...

Medical research

Breathless: How blood-oxygen levels regulate air intake

Researchers have unraveled the elusive process by which small, highly vascular clusters of sensory cells in the carotid arteries "taste the blood," as a 1926 essay put it—the initial step in regulating blood-oxygen levels.

Parkinson's & Movement disorders

A hopeful new strategy for treating Parkinson's disease

A novel compound developed by a team led by the University of Colorado Boulder may be therapeutic in suppressing misguided inflammatory responses by a set of immune cells known as microglia to perceived damage to the brain ...

Medical research

Why too much DNA repair can injure tissue

DNA-repair enzymes help cells survive damage to their genomes, which arises as a normal byproduct of cell activity and can also be caused by environmental toxins. However, in certain situations, DNA repair can become harmful ...

Cancer

Researchers characterize mechanism of action of CAR T cells

The scientific community has made great strides over the past decade in the development of a new class of cancer therapy called immunotherapy, a treatment that activates a patient's own immune system to target cancer cells. ...

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