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Medications
Clinical trial highlights promising new treatment for intestinal worms
A new tablet combining albendazole and ivermectin is safe and more effective than albendazole alone in treating Trichuris trichiura and other soil-transmitted helminths (STH), according to a clinical trial conducted by the ...
Jan 10, 2025
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Medications
Study reveals cost differences between Medicare Advantage and traditional Medicare patients in cancer drugs
A new study examining the use of high-cost drugs among patients with colorectal cancer and non-small cell lung cancer found those insured through Medicare Advantage received less expensive cancer drugs compared to others ...
Jan 10, 2025
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Medicare rules may reduce prescription steering
Weill Cornell Medicine researchers have found that pharmacy benefit managers (PBMs)—organizations that negotiate access to medicines for most patients in the United States—steer patients to use their own pharmacies. However, ...
Jan 10, 2025
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Data-driven study reveals falling use of antiseizure drug in pregnancy
University of Liverpool researchers have contributed to the largest study to date on sodium valproate use. This significant report shows decreased use in women of childbearing age and during pregnancy, as well as young men, ...
Jan 10, 2025
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New drug for prostate cancer patients in clinical trials
Prostate cancer that has become resistant to hormone therapy could be treated using a new drug that is currently in clinical trials for ovarian and bile duct cancer, according to research published in the journal Clinical ...
Jan 10, 2025
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Some maternal medications lower levels of protein, fat in breastmilk
Some maternal medications are associated with lower levels of protein and fat in breastmilk, according to a study published online Jan. 7 in JAMA Network Open.
Jan 10, 2025
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Tuberculosis research: Scientists demonstrate effectiveness of a new antibiotic
A consortium including scientists from the Tropical Institute at LMU University Hospital has demonstrated the effectiveness of a new antibiotic. Tuberculosis is the most common infectious disease worldwide. In the year 2022 ...
Jan 9, 2025
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PCT blood test does not lower antibiotic treatment duration for hospitalized children, study shows
A new U.K. study led by the University of Liverpool has examined whether an additional blood test called procalcitonin (PCT) could safely shorten the time children spend on intravenous (IV) antibiotics in hospitals.
Jan 9, 2025
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Oral glucose-lowering agents are potential alternatives to insulin for gestational diabetes
With respect to the proportion of infants born large for gestational age, treatment of gestational diabetes with metformin and glyburide, if needed, does not meet the criteria for noninferiority versus insulin, according ...
Jan 9, 2025
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Talquetamab plus teclistamab shows promise in multiple myeloma
For patients with relapsed or refractory multiple myeloma, talquetamab plus teclistamab shows response in a high percentage of patients and a higher incidence of grade 3 or 4 infections than with either therapy alone, according ...
Jan 9, 2025
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Extended nirmatrelvir/ritonavir found to be beneficial for some with long COVID
Extended-course nirmatrelvir/ritonavir yields a meaningful reduction in symptoms for some patients with long COVID, but not all benefits persist, according to a case series published online Jan. 6 in Communications Medicine.
Jan 9, 2025
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Systematic review finds potential in glutamatergic medications for OCD treatment
A systematic review and meta-analysis from the Harvard T.H. Chan School of Public Health reported a large effect of glutamatergic medications on improving symptoms of obsessive-compulsive and related disorders (OCRDs). The ...
High-cost outliers distort public discussions about drug development costs, study says
The typical cost of developing new medications may not be as high as generally believed, with a few ultra-costly medications skewing public discussions about the cost of pharmaceutical research and development, according ...
Jan 7, 2025
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Incident gabapentin use not linked to increase in falls vs. duloxetine
Incident use of gabapentin is not associated with an increase in fall-related hospital visits compared with duloxetine use, according to a study published online Jan. 7 in the Annals of Internal Medicine.
Jan 7, 2025
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Approved drug dronedarone found to inhibit the proliferation of esophageal squamous cell carcinoma
Esophageal squamous cell carcinoma (ESCC) is a severe health threat, being a predominant subtype of esophageal cancer and contributing significantly to cancer-related mortality globally. Despite advancements in combination ...
Jan 7, 2025
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GLP-1 RAs efficacious for weight loss in overweight, obesity without diabetes
For adults with overweight or obesity without diabetes, glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are efficacious for weight loss, according to a review published online Jan. 7 in the Annals of Internal Medicine.
Jan 7, 2025
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Denosumab found to increase cardiovascular risk in dialysis-dependent patients
For dialysis-dependent patients treated for osteoporosis, denosumab is associated with a greater preventive effect on fractures but an increased risk for major adverse cardiovascular events (MACE) compared with oral bisphosphonates, ...
Jan 7, 2025
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Opioid disposal kits found to boost safe medication disposal by more than 10%
Extra opioid pain medications after surgeries are a concern because they increase the likelihood of their misuse, so researchers are intent on discovering ways to cut down on the medicines that could be left after recovery ...
Jan 7, 2025
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Extended Paxlovid may help some people with long COVID
An up-close look at how patients respond to the drug at different times and doses adds nuance to a recent finding that Paxlovid does not work for long COVID.
Jan 6, 2025
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DoxyPEP use linked to sharp decline in STI cases
A new study has found that rates of chlamydia and syphilis plummet among people prescribed doxycycline for sexually transmitted infection prevention in routine clinical care.
Jan 6, 2025
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Tuberculosis strains resistant to new drugs are being transmitted between patients, study finds
Tuberculosis (TB) is the world's biggest infectious disease killer, with multidrug-resistant TB (MDR-TB) posing a particular threat to global health. A study led by the Swiss Tropical and Public Health Institute (Swiss TPH) ...
Jan 6, 2025
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How legal pot may be reducing opioid prescriptions
In states where medical marijuana is legal, payments from opioid manufacturers to physicians have decreased significantly—suggesting that marijuana may be emerging as a viable alternative to opioids for pain management, ...
Jan 6, 2025
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Three drugs that went from legal, to illegal, then back again
Cannabis, cocaine and heroin have interesting life stories and long rap sheets. We might know them today as illicit drugs, but each was once legal.
Jan 6, 2025
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Will AI revolutionize drug development? Researchers explain why it depends on how it's used
The potential of using artificial intelligence in drug discovery and development has sparked both excitement and skepticism among scientists, investors and the general public.
Jan 6, 2025
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Preserving muscle with GLP-1 weight loss drugs: Big deal or nothing to worry about?
On the surface, the formula for weight loss seems simple: eat less and move more.
Jan 6, 2025
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