Temporal lobe epilepsy (TLE) is one of the most common types of epilepsy worldwide. Although symptomatic medications are available, one-third of TLE patients remain unresponsive to current treatment, so new drug targets are ...
Nov 23, 2022
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41
Scientists have revealed the inner workings of a key protein involved in a wide range of cellular processes—potentially paving the way for better and less toxic cancer drugs.
Nov 23, 2022
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75
In early 2020, Eric Pringle and Brett Duguay found themselves spending much of their time in their microbiology lab on the seventh floor of Dal's Tupper Building. The virologists were busy testing potential antivirals for ...
Nov 23, 2022
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75
After statins, the next leading class of medications for managing cholesterol are PCSK9 inhibitors. These highly effective agents help the body pull excess cholesterol from the blood, but unlike statins, which are available ...
Nov 17, 2022
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70
Johns Hopkins Medicine researchers have revamped an anti-cancer drug to better target cancer cells and leave healthy tissues unharmed. Scientists have dubbed this type of targeted approach a "prodrug"—a medicine designed ...
Nov 16, 2022
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1583
The complement system defends the body against microbial intruders, but it can also attack the body's own cells for various reasons and therefore contribute to clinical complications. These complications range from age-related ...
Nov 16, 2022
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53
After Alzheimer's, Parkinson's is the most common neurodegenerative disease in the world. More than six million people worldwide suffer from it. In this disease, alpha-synuclein proteins form thread-like structures called ...
Nov 15, 2022
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980
Researchers at the Technion—Israel Institute of Technology have developed a technique to measure the long-term effects of antibiotic combinations, or cocktails. These combinations are of serious interest to the scientific ...
Nov 14, 2022
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36
According to a study, type 1 diabetes could be prevented by inhibiting a gene associated with the onset of the disease. A drug based on the same mechanism has already been approved for the treatment of another autoimmune ...
Nov 9, 2022
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71
An interdisciplinary research team led by UCLA found that a drug already approved by the Food and Drug Administration for eye disease, verteporfin, stopped the replication of SARS-CoV-2, the virus that causes COVID-19. Their ...
Nov 8, 2022
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51
