MeSH tree: D12.776.157.687.375
Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the host's cellular machinery to make new copies of themselves. Herpes simplex virus-1 (HSV-1), it turns ...
Jun 19, 2025
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Scientists have discovered how interactions between RNA and the TOP1 essential enzyme, which is overexpressed in many human cancers, regulate DNA during transcription and may inform the creation of new cancer therapies, according ...
Aug 22, 2024
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A research group at the University of Bologna has identified, for the first time, the specific location and genomic context where DNA breaks occur due to the inhibition of the topoisomerase I, a protein crucial for many biological ...
Aug 8, 2024
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Northwestern Medicine scientists have discovered new insights into the production and regulation of a class of noncoding RNAs and how alterations in their signatures diversify and modulate the transcriptome of three major ...
Aug 5, 2024
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A new publication in Science Advances from researchers at Karolinska Institutet shows how to use a specific cancer trait to improve treatment of pancreatic tumors.
Nov 1, 2023
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A new research paper has been published in the journalOncotarget entitled, "Diphenyl ditelluride anticancer activity and DNA topoisomerase I poisoning in human colon cancer HCT116 cells." Diphenyl ditelluride (DPDT) is an ...
Jun 26, 2023
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The structure of chromatin—the mixture of DNA and proteins that form chromosomes—can affect gene expression, and certain chromatin "readers" are important for monitoring this structure often in response to environmental ...
Aug 22, 2022
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