Powerful antioxidant resveratrol prevents metabolic syndrome in lab tests: study

September 2, 2011

Researchers in the Faculty of Medicine & Dentistry at the University of Alberta have discovered that resveratrol, a powerful antioxidant found in common foods, prevents a syndrome in some offspring that could lead to later health issues such as diabetes.

Resveratrol is found in fruits, nuts and red wine, and has been shown to extend the lifespan of many species.

Human offspring that have trouble growing in the womb have an increased risk of developing metabolic problems later in life. But U of A medical researchers Jason Dyck and Sandra Davidge and their teams found that administering to the young offspring of lab rats after weaning actually prevented the development of a metabolic syndrome, which is characterized by glucose intolerance, and higher deposits of abdominal fat.

Dyck and Davidge published their findings in a recent edition of the peer-reviewed journal Diabetes. Dyck is a researcher in the departments of Pediatrics and Pharmacology, while Davidge is a researcher in the departments of Obstetrics & Gynecology and Physiology. Both are also members of the Mazankowski Alberta Heart Institute, as well as the Women and Children’s Health Research Institute. Dyck and Davidge were co-senior authors of the study.

The study took advantage of the fact that "infancy is a potential window of opportunity to intervene and prevent the future development of metabolic diseases." The researchers noted this is the first potential pharmacological treatment that may help babies that developed in a growth-restricted environment in the womb.

"There is a concept that in utero, there are genetic shifts that are occurring – reprogramming is occurring because of this strenuous environment babies are in, that allows them to recover very quickly after birth," says Dyck.

"When babies are growth-restricted, they usually have a catch-up period after they are born where they catch up to non-growth-restricted groups. It might be that reprogramming that creates this kind of 'thrifty' phenotype, where they want to consume and store and get caught up.

"That reprogramming appears to make them more vulnerable to developing a host of metabolic problems."

Earlier this year, Dyck and Davidge published another paper in Diabetes demonstrating that rat offspring not growing well in the womb had noticeable side effects from high-fat diets after birth – the rats deposited more fat in the abdominal area, developed glucose intolerance, more dramatic cases of insulin resistance and insulin resistance at earlier stages of life.

Dyck and Davidge are continuing their research in this area, examining whether treating the mother during pregnancy can prevent metabolic problems in rat offspring affected by intrauterine growth restriction.

Davidge is an Alberta Innovates-Health Solutions (AIHS) Scientist and a Canada Research Chair in Women’s Cardiovascular Health. Dyck is an AIHS Senior Scholar and the Director of the Cardiovascular Research Centre at the U of A.

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2.3 / 5 (3) Sep 02, 2011
This is nice and honest, but does anyone really care. We already know that the difference between those societies that consume animal products and those that don't; it is an almost complete absence of heart disease, cancer, diabetes, obeseness, and possibly many others. This has been common sense for a long, long time. Let's not pretend this is new. It is a stated fact that many people do not want to hear. Like how 80% of the red blood cells from slaughtered cows are fed to the dairy cows as nourishment. Come on, man is out of control and these tidbits of rational thought, although welcome, fails to address the fundamental fact, man already knows and he is pretending he doesn't. The same people are passing around the same lies and are the ones jumping from jobs at the epa, fda and the agra companies. Keep talking the same bs, blah blah animal product is healthy this or that. For heart disease, the #1 killer in the USA,it is almost 100% prevented/cured with not using any animal product.
5 / 5 (1) Sep 02, 2011
not rated yet Sep 02, 2011
2.3 / 5 (3) Sep 02, 2011
I've been a vegetarian for a couple of years now and I believe my health condition is better than it's ever been. I supplement with methylcobalamin (a superior form of B12) and acetyl L-carnitine so it covers what may be missing in my diet. I used a rest room in a Home Depot recently and was asphyxiated by the stench from an obvious meat eater. I was in such a hurry to escape I found myself zipping up my fly outside. I'm not a snob, but "I think my shit don't stink!" since I stopped eating meat.
3 / 5 (2) Sep 04, 2011
I've been a vegetarian for a couple of years now and I believe my health condition is better than it's ever been.
But as I have pointed out before your brain doesnt seem to be functioning very well. You yourself seem to accept that your leaf-eating is unnatural because you need to supplement it in order to get the proper nutrition.

And your subjective analysis of restroom gasses does not consider the actual diet of your antagonist or a chemical analysis of his offal which would be essential in proper diagnosis. Perhaps the odor was the result of guacamole and jalapeno? Rotting cucumber is the worst smell on the planet.

You have also been seeing cigar-shaped UFOs which has decidedly freudian implications.
1 / 5 (3) Sep 04, 2011
Veggietarians are simpleton idealists and fantasy dwellers:

-Did you know that the favorite food of many african indigenes is bushmeat; that being primate meat? Ape flesh is closest to human flesh in composition. We apparently have a taste for it.

Humans evolved in the context of a million or so years of near-constant tribal war caused by chronic overpopulation and conflict over resources.

This warfare usually involved stalking and ambushing enemy tribesmen. And why leave all that good protein strewn about for mans natural enemies to consume, when the people back at camp needed food? Hunting and fighting in this context are identical in nature.

Humans were habitual cannibals, from necessity and later from preference. We have developed immunity to certain prion diseases as a result. Much evidence for this.

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