Prenatal exposure to combustion-related pollutants leads to anxiety, attention problems in young children

March 22, 2012, Columbia University

Mothers' exposure during pregnancy to a class of air pollutants called polycyclic aromatic hydrocarbons (PAH) can lead to behavioral problems in their children. PAH are released to air during incomplete combustion of fossil fuel such as diesel, gasoline, coal, and other organic material.

The study is the first report of associations between child attentional and behavioral problems among school‐age children and two complementary measures of prenatal exposure: monitored air concentrations of PAH and a PAH-specific biomarker of exposure measured in maternal and umbilical cord blood. The paper, "Prenatal Polycyclic Aromatic Hydrocarbon (PAH) Exposure and Child Behavior at age 6-7," published online today in Environmental Health Perspectives, adds to rising concerns about the risks associated with exposures to air pollution during pregnancy.

The study followed the children of 253 non‐smoking inner-city women who gave birth between 1999 and 2006. Researchers led by Frederica Perera, DrPH, director of the Columbia Center for Children's Environmental Health at the Mailman School of Public Health, measured two complementary indicators of PAH exposure. One indicator was the PAH concentration in air from personal air sampling which took place during the third trimester of pregnancy. The other was a specific biological marker of exposure-- PAH–DNA adducts measured in maternal blood and newborn umbilical cord blood. When inhaled by the mother during , PAH can be transferred across the placenta and bind to the DNA of the fetus, forming "adducts" in blood and other tissues and providing a biologic measure of pollutant exposure.

Mothers completed a detailed assessment of their child's behavior (including whether the children experienced symptoms of anxiety, depression, or attention problems. High prenatal PAH exposure, whether characterized by personal air monitoring or maternal and newborn cord adducts, was significantly associated with symptoms of Anxious/Depressed and Attention Problems.

In urban air, traffic emissions are a dominant source of the pollutants measured in the study. Illustrating widespread exposure to these pollutants, 100% of the mothers in the Columbia Center for Children's Environmental Health NYC cohort had detectable levels of PAH in prenatal personal air samples, although levels varied widely. The authors accounted for other sources of PAH such as environmental tobacco smoke and diet in their analyses. None of the mothers in the study were smokers.

"This study provides evidence that environmental levels of PAH encountered in NYC air can adversely affect child behavior. The results are of concern because attention problems and anxiety and depression have been shown to affect peer relationships and academic performance," said Dr. Perera, the study's lead author.

Explore further: Prenatal exposure to certain pollutants linked to behavioral problems in young children

Related Stories

Prenatal exposure to certain pollutants linked to behavioral problems in young children

April 12, 2011
Mothers' exposure during pregnancy to pollutants created by the incomplete combustion of fossil fuels and other organic material may lead to behavioral problems in their children, according to a new study. Researchers found ...

Pregnant mothers at risk from air pollution

October 7, 2011
A Californian-based study has looked in detail at air quality and the impact of traffic-related air pollution on premature birth. Published in BioMed Central's open access journal Environmental Health, results from this study ...

Recommended for you

Potential for sun damage should be carefully balanced with need for vitamin D in children, say scientists

April 24, 2018
Scientists at King's College London are encouraging parents and carers to ensure even more rigorous protection of children against the harmful effects of the sun. The comments follow a study which has suggested that children ...

Drinking affects mouth bacteria linked to diseases

April 24, 2018
When compared with nondrinkers, men and women who had one or more alcoholic drinks per day had an overabundance of oral bacteria linked to gum disease, some cancers, and heart disease. By contrast, drinkers had fewer bacteria ...

Millennials aren't getting the message about sun safety and the dangers of tanning

April 24, 2018
Many millennials lack knowledge about the importance of sunscreen and continue to tan outdoors in part because of low self-esteem and high rates of narcissism that fuel addictive tanning behavior, a new study from Oregon ...

People expect their memory to fade as early as their 50s

April 24, 2018
People across the UK expect their memory to worsen in their 50s, according to new research from Heriot-Watt University.

Aging: The natural stress reliever for many women

April 24, 2018
While some research suggests that midlife is a dissatisfying time for women, other studies show that women report feeling less stressed and enjoy a higher quality of life during this period.

Napping and teenage learning

April 24, 2018
Teenagers and sleep. It's certainly a passionate subject for many American parents, and those in China. University of Delaware's Xiaopeng Ji is investigating the relationship between midday-napping behaviors and neurocognitive ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.