Bone metabolism, vitamin D key in postkyphoplasty breaks

April 25, 2012
Bone metabolism, vitamin D key in postkyphoplasty breaks

(HealthDay) -- For postmenopausal women with osteoporosis, bone metabolism and 25-hydroxyvitamin D (25[OH]D) levels are associated with postkyphoplasty recurrent vertebral compression fractures, according to a study published online April 12 in The Spine Journal.

To investigate the incidence of recurrent fractures after , Christos P. Zafeiris, M.D., of the University of Athens in Greece, and colleagues conducted a prospective study of 40 postmenopausal women (mean age, 70.6 years) with osteoporosis and acute symptomatic vertebral compression fractures, who underwent a total of 98 kyphoplasties. The association between status of bone metabolism and 25(OH)D levels and fractures was examined. Patients were followed for 18 months.

After initial kyphoplasty, the researchers found that nine patients (22.5 percent) developed a vertebral compression fracture; in seven patients (17.5 percent), cement leakage was identified. Compared to patients with recurrent fractures, higher levels of 25(OH)D and lower N-terminal cross linked telopeptide values were seen in patients without recurrent factures.

" and 25(OH)D levels seem to play a role in the occurrence of postkyphoplasty recurrent ," the authors write.

Explore further: IOF urges systematic osteoporosis management after vertebral fracture augmentation

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

IOF urges systematic osteoporosis management after vertebral fracture augmentation

August 1, 2011
A working group of the International Osteoporosis Foundation (IOF) has issued a literature review of prospective controlled studies comparing the efficacy and safety of two minimally invasive techniques for vertebral augmentation ...

Heart failure patients' osteoporosis often undiagnosed, untreated

May 10, 2011
One in 10 heart failure patients had compression fractures in the spine that could have been detected by a chest X-ray, but few are receiving treatment to help prevent such fractures according to a Canadian study published ...

Recommended for you

Ambitious global virome project could mark end of pandemic era

February 23, 2018
Rather than wait for viruses like Ebola, SARS and Zika to become outbreaks that force the world to react, a new global initiative seeks to proactively identify, prepare for and stop viral threats before they become pandemics.

Forecasting antibiotic resistance with a 'weather map' of local data

February 23, 2018
The resistance that infectious microbes have to antibiotics makes it difficult for physicians to confidently select the right drug to treat an infection. And that resistance is dynamic: It changes from year to year and varies ...

Study reveals how kidney disease happens

February 22, 2018
Monash researchers have solved a mystery, revealing how certain immune cells work together to instigate autoimmune kidney disease.

Scientists gain new insight on how antibodies interact with widespread respiratory virus

February 22, 2018
Scientists have found and characterized the activity of four antibodies produced by the human immune system that target an important protein found in respiratory syncytial virus (RSV), according to new research published ...

Past encounters with the flu shape vaccine response

February 20, 2018
New research on why the influenza vaccine was only modestly effective in recent years shows that immune history with the flu influences a person's response to the vaccine.

Building better tiny kidneys to test drugs and help people avoid dialysis

February 16, 2018
A free online kidney atlas built by USC researchers empowers stem cell scientists everywhere to generate more human-like tiny kidneys for testing new drugs and creating renal replacement therapies.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.