Bone metabolism, vitamin D key in postkyphoplasty breaks

April 25, 2012
Bone metabolism, vitamin D key in postkyphoplasty breaks

(HealthDay) -- For postmenopausal women with osteoporosis, bone metabolism and 25-hydroxyvitamin D (25[OH]D) levels are associated with postkyphoplasty recurrent vertebral compression fractures, according to a study published online April 12 in The Spine Journal.

To investigate the incidence of recurrent fractures after , Christos P. Zafeiris, M.D., of the University of Athens in Greece, and colleagues conducted a prospective study of 40 postmenopausal women (mean age, 70.6 years) with osteoporosis and acute symptomatic vertebral compression fractures, who underwent a total of 98 kyphoplasties. The association between status of bone metabolism and 25(OH)D levels and fractures was examined. Patients were followed for 18 months.

After initial kyphoplasty, the researchers found that nine patients (22.5 percent) developed a vertebral compression fracture; in seven patients (17.5 percent), cement leakage was identified. Compared to patients with recurrent fractures, higher levels of 25(OH)D and lower N-terminal cross linked telopeptide values were seen in patients without recurrent factures.

" and 25(OH)D levels seem to play a role in the occurrence of postkyphoplasty recurrent ," the authors write.

Explore further: IOF urges systematic osteoporosis management after vertebral fracture augmentation

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

IOF urges systematic osteoporosis management after vertebral fracture augmentation

August 1, 2011
A working group of the International Osteoporosis Foundation (IOF) has issued a literature review of prospective controlled studies comparing the efficacy and safety of two minimally invasive techniques for vertebral augmentation ...

Heart failure patients' osteoporosis often undiagnosed, untreated

May 10, 2011
One in 10 heart failure patients had compression fractures in the spine that could have been detected by a chest X-ray, but few are receiving treatment to help prevent such fractures according to a Canadian study published ...

Recommended for you

Lung-on-a-chip simulates pulmonary fibrosis

May 25, 2018
Developing new medicines to treat pulmonary fibrosis, one of the most common and serious forms of lung disease, is not easy.

Reconstructing Zika's spread

May 24, 2018
The urgent threat from Zika virus, which dominated news headlines in the spring and summer of 2016, has passed for now. But research into how Zika and other mosquito-borne infections spread and cause epidemics is still very ...

Tick bite protection: New CDC study adds to the promise of permethrin-treated clothing

May 24, 2018
The case for permethrin-treated clothing to prevent tick bites keeps getting stronger.

Molecular network boosts drug resistance and virulence in hospital-acquired bacterium

May 24, 2018
In response to antibiotics, a gene regulation network found in the bacterium Acinetobacter baumannii acts to boost both virulence and antibiotic resistance. Edward Geisinger of Tufts University School of Medicine and colleagues ...

Past use of disinfectants and PPE for Ebola could inform future outbreaks

May 24, 2018
Data from the 2014 Ebola virus outbreak at two Sierra Leone facilities reveal daily usage rates for disinfectant and personal protective equipment, informing future outbreaks, according to a study published May 24, 2018 in ...

Early lactate measurements appear to improve results for septic patients

May 24, 2018
On October 1, 2015, the United States Centers for Medicare and Medicaid Services (CMS) issued a bundle of recommendations defining optimal treatment of patients suffering from sepsis, a life-threatening response to infection ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.